4-Bromoindole-2-carboxylic acid ethyl ester(CAS#103858-52-2)

Introduction

Ethyl 4-bromoindole-2-carboxylate is an organic compound. It is a derivative of indole in which the bromine atom replaces the carbon atom No. 4 of the indole ring and the ethyl acetate group replaces the carboxylic acid group on the carbon atom No. 2 of the indole ring.This compound is white to light yellow crystals at room temperature and is soluble in organic solvents such as ethanol and acetone, but insoluble in water. It has a medium to strong odor.The main use of ethyl 4-bromoindole-2-carboxylate is as an intermediate in organic synthesis.The preparation of ethyl 4-bromoindole-2-carboxylate is usually done by reacting indole with bromoacetic acid under suitable reaction conditions. This can be done by using a mixture of bromine and acetic acid to react directly with indole or by first converting indole into the corresponding salts and then reacting with bromoacetic acid.It can be irritating and damaging to the human body, and in the laboratory, personal protective equipment such as lab gloves and goggles should be used, and proper protocols should be followed. It should be stored in a cool, dry and airtight container, away from ignition and oxidants. In case of inhalation or contact with skin and eyes, wash immediately with water and seek medical attention immediately.