7-bromo-2-chloro-1-methyl-1H-benzimidazole(CAS#913297-43-5)
Key properties
Appearance: At room temperature, it is a white to light yellow crystalline powder (purity ≥ 98%) with no obvious odor;
Core characteristics: Easy to dissolve in polar organic solvents such as dichloromethane, tetrahydrofuran, DMSO, slightly soluble in ethanol and methanol, difficult to dissolve in water; Stable under room temperature sealing and light avoidance conditions, avoiding high temperature and contact with strong oxidants and alkalis;
Reactivity: Halogen atoms (Br, Cl) have good substitution reactivity and can react with nucleophilic reagents such as amines and thiols to construct complex heterocyclic structures.
3、 Main applications
As a key intermediate in the fields of medicine and pesticides, it is mainly used for the synthesis of active ingredients such as antifungal, antiviral, and anti-tumor drugs. It can also be used for the preparation of nitrogen-containing heterocyclic fine chemicals, achieving precise molecular structure construction through functional group modification.
4、 Safety and Storage
Danger: Inhalation or skin contact may cause slight irritation, avoid ingestion;
Storage requirements: Seal and store in a cool, dry, and ventilated place (temperature ≤ 30 ℃), away from heat sources and open flames. Use double-layer packaging (inner PE bag+outer cardboard bucket) to prevent moisture absorption and leakage;
Operation protection: Wear dust masks, nitrile gloves, and protective goggles to avoid direct contact.
