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Hydroxylamine hydrochloride(CAS#5470-11-1)

Chemical Property:

Molecular Formula NH2OH·HCl
Molar Mass 69.49
Density 1.67g/mLat 25°C(lit.)
Melting Point 155-157°C (dec.)(lit.)
Boling Point 56.5°C at 760 mmHg
Water Solubility 560 g/L (20 ºC)
Solubility Soluble in water, soluble in alcohol and glycerin, insoluble in cold water and ether.
Vapor Presure 0.054 Pa (50 °C)
Appearance White needle crystal
Color White to off-white
Merck 14,4828
BRN 3539763
PH 2.5-3.5 (25℃, 50mg/mL in H2O)
Storage Condition Store at +15°C to +25°C.
Stability Substances to be avoided include strong oxidizing agents. Heating above 115 C may cause explosion; do not store above 65C. Moisture and air sensitive.
Sensitive Hygroscopic
MDL MFCD00051089
Physical and Chemical Properties White Crystal, deliquescent, specific gravity (17 ℃)1.67
Use It is mainly used for reducing agents and imaging agents, for the preparation of oxime in organic synthesis, and also as a raw material for the synthesis of anticancer drugs (hydroxyurea), sulfa drugs (sulfamethoxazole) and pesticides (methomyl). It is used as a depolarization agent in Electroanalysis, a short-term stop agent for non-coloring in synthetic rubber industry, and the determination of acetal degree.

Product Detail

Product Tags

Risk Codes R22 – Harmful if swallowed
R36/38 – Irritating to eyes and skin.
R43 – May cause sensitization by skin contact
R48/22 – Harmful danger of serious damage to health by prolonged exposure if swallowed.
R50 – Very Toxic to aquatic organisms
R40 – Limited evidence of a carcinogenic effect
R21/22 – Harmful in contact with skin and if swallowed.
R2 – Risk of explosion by shock, friction, fire or other sources of ignition
Safety Description S22 – Do not breathe dust.
S24 – Avoid contact with skin.
S37 – Wear suitable gloves.
S61 – Avoid release to the environment. Refer to special instructions / safety data sheets.
S36/37 – Wear suitable protective clothing and gloves.
UN IDs UN 2923 8/PG 2
WGK Germany 3
RTECS NC3675000
FLUKA BRAND F CODES 21
TSCA Yes
HS Code 28251000
Hazard Class 8
Packing Group III
Toxicity LD50 orally in mice: 408 mg/kg (Riemann)

 

Introduction

The following is a detailed introduction to the properties, uses, preparation methods and safety information of hydroxylamine hydrochloride:Quality:1. Hydroxylamine hydrochloride has the property of being miscible with water and can be soluble in organic solvents such as alcohols and ethers.2. It is reductive and reacts violently when reacting with oxidizing agents such as acidic potassium permanganate.3. Hydroxyamine hydrochloride is highly corrosive and can cause irritation and damage in contact with the skin and eyes.Use:1. Hydroxylamine hydrochloride is mainly used as a reducing agent and reagent in organic synthesis reactions. It is commonly used to reduce compounds such as nitrites, aldehydes, and ketones.2. Hydroxylamine hydrochloride can also be used to prepare other compounds, such as hydroxylamine hydrochloride, used as a rubber additive, antioxidant, etc.Preparation method:Hydroxylamine hydrochloride can be prepared by a variety of methods, two of which are commonly used:1. Ammonia reacts with hydrogen peroxide to obtain hydroxamine, and then reacts with hydrochloric acid to obtain hydroxylamine hydrochloride.2. Add ammonium sulfate and ammonia to alcohol, and heat it to produce ammonia, which reacts with hydrogen peroxide to form hydroxylamine, and then reacts with hydrochloric acid to form hydroxylamine hydrochloride.Safety Information:1. Hydroxylamine hydrochloride is corrosive and irritating, so you should pay attention to wearing protective glasses, gloves, clothing and other protective equipment when using it.2. Avoid contact with skin or eyes, and if accidentally touched, rinse immediately with plenty of water for at least 15 minutes, and seek medical attention if necessary.3. During use and storage, it should be kept away from fire and humid environments.4. Hydroxylamine hydrochloride is a dangerous product and should be stored in a sealed container away from other substances to prevent reaction with moisture in the air.


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