Nopyl Acetate (CAS: 128-51-8) is a natural terpene ester compound derived from turpentine deep processing. Its molecular structure combines the unique aroma of terpene skeleton with the chemical stability of ester group. As an important naturally derived fine chemical, it exhibits irreplaceable application value in green mosquito repellents, natural flavors and fragrances, and biopesticides. Its production relies on turpentine resource endowment, and market demand is closely related to the “natural and safe” product preference under consumption upgrading and the improvement of public health prevention and control system. Based on the resource attributes and industrial characteristics of this compound, this paper systematically analyzes its international market dynamics, focusing on core application scenarios, market competition pattern, regional development differences and future trends, so as to provide strategic reference for industry participants.
Core Application Fields and Demand
The market demand for Nopyl Acetate (CAS: 128-51-8) is highly concentrated in three major fields: green mosquito repellents, natural flavors and fragrances, and biopesticides. Its natural origin and environmental compatibility are the core advantages driving demand growth.
In the field of green mosquito repellents, as a high-efficiency and low-toxicity mosquito repellent ingredient, its protection rate against mosquitoes transmitting dengue fever exceeds 80%. With low irritation and mild odor, it can be harmoniously compatible with fragrances in mosquito repellent products. International daily chemical giants such as Johnson & Johnson and Kao have strict standards for the purity (≥98.5%) and biosafety of Nopyl Acetate in their natural series of mosquito repellent products, and their procurement volume accounts for more than 55% of the global market demand. With the upgrading of global dengue fever prevention and control needs and the improvement of consumers’ health awareness, the demand in this field maintains an annual growth rate of 7%-10%.
In the natural flavors and fragrances industry, Nopyl Acetate (CAS: 128-51-8) has a fresh pine needle-citrus compound aroma, making it an important component of natural daily chemical flavors and food flavors. It is widely used in men’s cologne, forest-style aromatherapy, mint-flavored food additives and other scenarios. International flavor giants Givaudan and IFF utilize the modification potential of its terpene structure to develop a variety of new aroma components through hydrogenation and oxidation reactions for high-end natural flavor formulations. With the tightening of EU Cosmetics Regulation (EC 1223/2009) on synthetic fragrances, the demand growth rate of naturally derived Nopyl Acetate is significantly higher than the industry average.
In the field of biopesticides, it has a good repellent effect on aphids and other pests, and is safe and harmless to beneficial insects, suitable for organic agriculture needs. It has been applied on a large scale in Brazil, India and other countries, and the demand for industrial-grade products is growing steadily, becoming a market supplement.
Major Market Participants
The global market supply system of Nopyl Acetate (CAS: 128-51-8) presents a pattern of “resource-based enterprises leading and technology-based enterprises breaking through in segments”. Due to the high dependence of production on turpentine resources and the need for high-end products to break through purification technology barriers, market competition is concentrated on enterprises with dual advantages of resource endowment and technical strength.
In the global high-end market, international enterprises with advantages in the turpentine deep processing industrial chain occupy a dominant position. Symrise of France, relying on its technical accumulation in natural terpene derivatives, can stably supply pharmaceutical-grade Nopyl Acetate with purity ≥99%. The product has passed EU ECOCERT natural certification and is mainly supplied to daily chemical giants such as Johnson & Johnson and Kao. International Flavors & Fragrances Inc. (IFF) of the United States, relying on its global advantage in flavor formulation, deeply integrates self-produced Nopyl Acetate into high-end flavor solutions to form a differentiated competitive advantage. Hayashibara of Japan optimizes the production process through biocatalysis technology, and its products excel in low irritation indicators, occupying more than 60% of the raw material market for infant mosquito repellent products in Japan.
In the industrial-grade and resource-based supply field, enterprises from countries rich in turpentine resources such as China and Brazil have become core forces. As the world’s largest turpentine producer, China has nurtured a number of backbone enterprises. Their products are mainly industrial-grade with purity of 97%-98%, and some enterprises have developed 99% purity products through molecular distillation technology. In terms of process characteristics, domestic enterprises have generally introduced continuous rectification and green catalytic esterification technologies, achieved breakthroughs in reducing the interference of turpentine acid value and improving product yield, and effectively controlled production costs. Forchem of Brazil, relying on South American resin resources, focuses on supplying Nopyl Acetate for biopesticides to the Latin American agricultural market.
Regional Market Dynamics
The global market demand for Nopyl Acetate (CAS: 128-51-8) presents regional differentiation characteristics of “Europe and the United States leading high-end consumption, Asia-Pacific leading production and growth, and Latin America and Africa driving basic demand”. North America, Europe, Asia-Pacific and Latin America together account for 95% of the global market size. Regional industrial division of labor and trade flows are significantly affected by resource distribution, consumption habits and public health policies.
Europe and the United States account for more than 75% of the global demand for high-end products, and the demand for daily chemical fragrances exceeds 60%. The U.S. natural daily chemical market size exceeds 8 billion US dollars annually, with strict requirements for product stability and safety; driven by regulations in Europe, organic brands in France and Germany have high demands for natural certification and compatibility, and enterprises such as Symrise improve response speed through localized production.
The Asia-Pacific region has developed into the global production hub and the fastest-growing consumer market for Nopyl Acetate (CAS: 128-51-8), with China, India and Southeast Asia forming the core region. As the world’s largest producer (annual output accounting for more than 70% of the global total), China not only supplies industrial-grade products to the world, but also has seen rapid release of domestic demand in recent years with the consumption upgrading of domestic mosquito repellent products (the market size of domestic natural mosquito repellent products increased by 15% year-on-year in 2024). India and Southeast Asia, relying on mosquito prevention and control needs under tropical climate, have become important consumer markets for industrial-grade Nopyl Acetate. The procurement volume of daily chemical enterprises in Indonesia, Thailand and other countries has an annual growth rate of 12%-15%, mainly used for the production of mid-to-low-end mosquito repellent sprays. Although the markets of Japan and South Korea are relatively small, the demand for high-end raw materials for infants and young children is stable, driving enterprises such as Hayashibara to layout high-purity product supply networks here.
Latin America and Africa are the engines of basic demand growth. The organic agriculture in Brazil and dengue fever prevention and control in South Africa have promoted the steady growth of demand for industrial-grade Nopyl Acetate. The regional market is highly price-sensitive, and local enterprises in China and Brazil occupy a dominant position with cost advantages, with an annual demand growth rate of 8%-10%.
Regulatory and Environmental Considerations
As a daily chemical raw material in direct contact with the skin and a potential food-contact flavor, the production, trade and use of Nopyl Acetate (CAS: 128-51-8) are subject to strict supervision by major global economies. Compliance certification has become a core threshold for entering the international market, and regulatory standards vary significantly across different application fields.
In the EU market, the compound must meet multiple regulatory requirements according to application scenarios: when used in mosquito repellent products, it needs to obtain approval as an active substance under the BPR Regulation (currently 8 enterprises have completed EU BPR registration); when used in cosmetics, it must comply with the EU Cosmetics Regulation (EC 1223/2009) to ensure that heavy metal residues (lead, arsenic, etc.) are below 1ppm; when used in food flavors, it needs to pass the safety assessment of the European Food Safety Authority (EFSA) and be included in the “List of Flavorings Allowed for Use in Food in the EU”. Non-EU manufacturers must fulfill compliance obligations through an Only Representative (OR) in the EU, and compliance costs are 30%-50% higher than those of ordinary chemicals.
In the U.S. market, Nopyl Acetate (CAS: 128-51-8) for mosquito repellent use needs to complete biopesticide registration with the U.S. Environmental Protection Agency (EPA) and submit complete efficacy test and toxicological data; products for cosmetic use must comply with the safety assessment standards of the Cosmetic Ingredient Review (CIR); food-use products must comply with the requirements for food additives in Title 21 of the Code of Federal Regulations (21 CFR) of the FDA, and a component purity test report must be provided for import. Violations of relevant regulations may result in product recalls and fines of up to 1.5 million US dollars.
In the Asian market, China has included it in the list of allowed raw materials in the Safety and Technical Standards for Cosmetics (2015 Edition) and implemented a safety production licensing system for manufacturers; Japan regulates daily chemical and food-use products through the Cosmetics Act and the Food Sanitation Act respectively, requiring complete raw material traceability reports; India implements registration management for Nopyl Acetate for mosquito repellent use through the Insecticides Act. In international trade, as a flammable liquid (flash point 86℃), the compound must be packed in compliance with the International Maritime Dangerous Goods Code (IMDG Code).
Environmentally, the global trend of green chemical industry is driving the upgrading of production processes. The waste acid emission problem in traditional turpentine esterification processes has become the focus of supervision. The EU REACH Regulation has listed relevant processes as “environmental risk processes requiring priority improvement”, promoting enterprises to adopt green processes such as solid acid catalysis.
Future Outlook
The market prospect of Nopyl Acetate (CAS: 128-51-8) is closely linked to the development of three major fields: green daily chemicals, public health prevention and control, and organic agriculture. The global consumption trend of “natural replacing synthetic” and the expansion of emerging market demand will become core growth drivers. It is expected that the global market size will maintain a compound annual growth rate of 8%-10% in the next 5 years.
On the demand side, three major growth drivers are clear: first, the upgrading of green daily chemical consumption. Global consumers’ preference for low-irritation and naturally derived daily chemical products continues to strengthen, especially in segmented fields such as infant care and high-end outdoor protection, which will drive the demand for high-purity Nopyl Acetate; second, the normalization of public health prevention and control. The demand for tropical infectious disease prevention and control promotes the popularization of mosquito repellent products in Southeast Asia, Africa and other regions, driving the consumption of industrial-grade products; third, the development of organic agriculture. The global organic planting area increases by 12% annually, promoting the steady growth of demand for Nopyl Acetate in biopesticides.
Challenges include: turpentine price fluctuations of 30%-40%; tightening regulations in various countries raising compliance costs; synthetic terpene esters seizing the mid-to-low-end market. Enterprises need to improve compatibility through process optimization, lock in resources to hedge risks, and build a global compliance system to respond.
To address the above challenges, enterprises should focus on improving compatibility capabilities: at the technical level, optimize processes to improve product purity and aroma stability, and enhance compatibility with high-end flavor formulations; at the supply chain level, establish long-term cooperation mechanisms for turpentine resources to hedge the risk of raw material price fluctuations; at the compliance level, build a global compliance service system to quickly respond to regulatory requirements in different regions.
In summary, Nopyl Acetate (CAS: 128-51-8), as a high-compatibility ingredient in daily chemical fragrances, has prominent value, and its demand is growing rapidly driven by “natural, safe and high-compatibility”. Despite challenges, technological upgrading and scenario expansion make its prospects promising. In the future, enterprises with resource integration, high-end purification and compliance service capabilities will lead the industry development.
Shanghai XinChem Co., Ltd. (XinChem)
As a world-leading supplier of organic chemicals, Shanghai XinChem Co., Ltd. (XinChem) has always focused on the innovative needs of the pharmaceutical, flavor, daily chemical and materials industries. Relying on core technological advantages in the synthesis and derivation of terpene compounds, we provide high-quality Nopyl Acetate (CAS: 128-51-8) to global customers. Synthesized from natural terpenes, the product combines unique aroma characteristics with excellent chemical stability, fully complying with strict standards in the food, daily chemical and pharmaceutical industries, and is an ideal choice in the field of functional fine chemicals.
1. Technical Advantages
Green Synthesis Process
Relying on the natural turpentine deep processing technology system, we have developed an optimized process for directional esterification of terpenes, combined with molecular distillation purification technology, to achieve dual improvements in product quality and production efficiency:
Using natural Nopyl Acetate (CAS: 128-51-8) as the starting material, an efficient catalytic system is adopted to precisely control the esterification reaction. The content of by-products is less than 0.3%, and the raw material conversion rate is increased to more than 98%, significantly reducing production costs.
Trace terpene isomers are removed through molecular distillation technology, resulting in excellent product aroma purity and component stability. The difference in key indicators between batches is controlled within 0.1%, meeting the needs of refined applications.
Full-Chain Compliance Control
The production process strictly complies with domestic and foreign regulatory standards such as FCC (Food Chemicals Codex), EU No 1334/2008 and China’s GB 2760. For the characteristics of terpene ester products, a full-chain quality control system covering raw material traceability, in-process testing and finished product release has been established. Green solvents are used to replace highly toxic solvents in traditional processes, with a solvent recovery rate of more than 95%. The carbon emission per unit product is 30% lower than the industry average, practicing the development concept of “natural origin and green manufacturing”.
2. Product Advantages
High Purity and Stable Aroma
The product purity is 95%/99% (GC detection), ensuring a clear woody aroma with citrus notes and excellent reaction selectivity in flavor blending and fine synthesis, avoiding the interference of impurities on product flavor or performance.
Diversified Packaging and Compatibility
Flexible packaging solutions are provided, including food-grade 180KG galvanized iron drums (for industrial large-scale applications), 25KG food-grade plastic drums (for pilot and batch production), and 1KG/5KG sealed aluminum bottles (for laboratory research and development and small-batch blending), adapting to the usage needs of different scenarios such as flavor and daily chemicals, pharmaceutical intermediates, and functional materials.
Reliable Supply Chain Guarantee
Relying on the turpentine deep processing industrial base, the annual production capacity of Nopyl Acetate reaches 200-300 tons, which can meet the demand for large-scale and stable supply. An exclusive normal-temperature and light-shielded storage and transportation system has been established (the product should be stored in a cool and dry place, avoiding high-temperature exposure, and the storage temperature should be controlled at 5-30℃).
3. Application Fields
As a naturally derived terpene ester compound, Nopyl Acetate (CAS: 128-51-8) exhibits wide application value in various fields due to its unique aroma characteristics and chemical reactivity, mainly including:
Flavor and Daily Chemical Field: Used as a core fragrance raw material in formulating daily chemical products with pine, coniferous, forest and other fragrances, such as soap, body wash, air freshener and industrial deodorant; used as a fixative in high-end perfumes to enhance aroma layering and durability; in tobacco flavors, it can improve smoke taste and reduce irritation.
Pharmaceutical and Food Field: Used as a pharmaceutical excipient in the preparation of solvents and stabilizers for external preparations, and its natural origin reduces the risk of skin irritation; used in food flavors to formulate mint, citrus and other compound flavors, suitable for chewing gum, baked food and functional beverages, complying with food additive use standards.
Functional Materials Field: Used as a monomer in the synthesis of terpene-based polymer materials to improve the weather resistance and biodegradability of materials, applied in environmentally friendly coatings, adhesives and packaging materials; used in the preparation of natural antibacterial agents for antibacterial treatment of textile fabrics and food packaging.
Agriculture and Daily Chemical Auxiliaries Field: Used in the synthesis of synergists for plant-derived pesticides to enhance the adhesion and penetration capacity of pesticide active ingredients; used as an emulsifying stabilizer in daily chemical products to improve the stability and skin feel of emulsion systems.
4. Service Support
Customized Technical Solutions
A team of senior flavor chemistry and application engineers provides full-process technical support. Based on the esterification, addition, polymerization and other reaction characteristics of Nopyl Acetate, we offer professional suggestions such as optimization of fragrance blending ratio and setting of reaction process parameters for customers, solve technical problems in product application, and customize exclusive solutions.
5. Reasons to Choose XinChem
Professionalism: 20 years of experience in the chemical industry.
Flexibility: We can adapt to any customer needs.
Cost – effectiveness: A perfect combination of high quality and competitive prices.
Contact us now to start cooperation!
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Post time: Dec-02-2025