Ethyl 2-methyl-3,4-pentadienoate (CAS: 60523-21-9) is a vital unsaturated carboxylate compound with a conjugated diene structure. As a key fine chemical intermediate, it exhibits unique application value in flavor & fragrance synthesis, pharmaceutical intermediate production, and functional material R&D, thanks to its reactive double bonds and ester functional groups. Boasting stable chemical properties and controllable reactivity, its global market demand is profoundly influenced by the production layouts and technological innovation strategies of international flavor giants, pharmaceutical R&D enterprises, and specialty chemical suppliers. Based on the industrial characteristics of this compound, this report systematically analyzes its international market dynamics, focusing on core application scenarios, major market participants, regional development features, and future trends, aiming to provide references for industry stakeholders.
Demand in Core Application Fields
The market demand forEthyl 2-methyl-3,4-pentadienoate (CAS: 60523-21-9) is highly concentrated in three major sectors: flavor & fragrance, pharmaceutical chemicals, and functional materials.
In the flavor & fragrance industry, the compound serves as a core precursor for synthesizing tropical fruit-flavored essences. Through condensation reactions with alcohols and aldehydes, it can produce characteristic aroma components mimicking natural mango and pineapple, which are widely used in food additives and daily chemical fragrances (e.g., shampoos, perfumes). International flavor giants such as Givaudan and Firmenich impose stringent standards on the aroma threshold stability and impurity control of ethyl 2-methyl-3,4-pentadienoate for manufacturing high-end natural-identical flavors, accounting for over 40% of global market demand. Driven by consumers’ growing preference for natural and safe fragrances, the demand for green flavor products synthesized from this compound maintains an annual growth rate of 5%-8%.
In the pharmaceutical chemical sector, the compound’s application as an intermediate for anti-inflammatory and anti-tumor drugs is increasingly prominent. Its conjugated structure can act as an active backbone for drug molecules, and targeted modification via epoxidation and hydrogenation reactions enhances drug targeting.
In the functional materials field, as a comonomer, it copolymerizes with acrylates, styrene, etc., to produce functional polymers with excellent weather resistance and elasticity, used for modifying coatings, adhesives, and other products. With the rising performance requirements for materials in new energy vehicle exterior coatings and high-end architectural adhesives, the demand for high-purity ethyl 2-methyl-3,4-pentadienoate shows a steady growth trend.
Major Market Participants
The global supply system ofEthyl 2-methyl-3,4-pentadienoate (CAS: 60523-21-9) presents a pattern of “dominance by specialized fine chemical enterprises supplemented by regional chemical manufacturers.” As a niche intermediate, it features complex production processes and limited economies of scale, resulting in low participation from international petrochemical giants. Market competition is concentrated among fine chemical enterprises with customized production capabilities.
In the global high-end market, BASF (Germany), Sigma-Aldrich (USA), and Daicel (Japan) hold leading positions. Leveraging mature precision production technologies (e.g., continuous distillation, directed catalytic synthesis), these enterprises stably supply high-specification products with purity ≥99%, meeting the high-end demands of flavor & fragrance and pharmaceutical R&D.
In the industrial-grade supply segment, chemical enterprises from emerging markets such as China and India serve as important supplementary forces.
Regional Market Dynamics
The global demand for Ethyl 2-methyl-3,4-pentadienoate (CAS: 60523-21-9) exhibits distinct regional differentiation: “Europe and North America dominate high-end consumption, while Asia-Pacific leads production growth.” North America, Europe, and Asia-Pacific constitute the three core markets, accounting for 92% of the global market size, with clear industrial division of labor and trade flows among regions.
North America and Europe are the core consumption regions for high-purity ethyl 2-methyl-3,4-pentadienoate, jointly accounting for over 70% of global high-end product demand. Benefiting from advanced food processing and pharmaceutical R&D industries (supported by a sound FEMA certification system), North America has become a major procurement base for enterprises like Givaudan and Pfizer. The market imposes strict requirements on product compliance (e.g., FDA certification) and traceability, driving suppliers to continuously improve production quality control. Influenced by the EU’s Food Additives Regulation (EFSA), the European market adopts more rigorous safety assessment standards for flavor raw materials. Localized production layouts by enterprises such as BASF and Firmenich (e.g., BASF’s Ludwigshafen production base in Germany) further consolidate their market advantages.
Asia-Pacific has evolved into the primary production base and growth-oriented consumption market for ethyl 2-methyl-3,4-pentadienoate, with China, Indonesia, and Thailand as core regions. As the industrial hub of the region, China is not only the world’s largest producer of industrial-grade products (accounting for over 60% of global annual output) but also one of the fastest-growing consumption markets globally, with a 12% year-on-year increase in market size in 2024, driven by the upgrading of the domestic food industry (e.g., expansion of the prepared food sector) and increased investment in pharmaceutical R&D. Supported by the booming food processing industry (e.g., Indonesia’s instant noodle manufacturing and Thailand’s fruit processing), Southeast Asia’s demand for industrial-grade products grows significantly faster than the global average (10%-12% annually) and is expected to become a key engine for global market growth in the next five years. Additionally, although Japan and South Korea have smaller consumption scales, their stable demand for high-purity pharmaceutical-grade products has prompted enterprises like Daicel to deploy high-end supply networks in these regions.
Regulatory and Environmental Considerations
As a food-contact chemical and pharmaceutical intermediate raw material, the production, trade, and use of Ethyl 2-methyl-3,4-pentadienoate (CAS: 60523-21-9) are subject to strict regulation by major global economies. Compliance certification has become a core threshold for enterprises entering the international market, with differentiated regulatory standards across application fields.
In the EU market, the compound must meet dual regulatory requirements based on application scenarios: for food flavors, it requires EFSA safety assessment and inclusion in the “EU List of Permitted Food Additives” (E1500 series); for industrial use, it must comply with the Registration, Evaluation, Authorization, and Restriction of Chemicals (REACH) Regulation. Enterprises placing over 1 ton of the substance on the market annually must complete substance registration, and non-EU manufacturers must fulfill compliance obligations through an Only Representative (OR). To date, 12 enterprises have completed REACH registration for this substance.
In the US market, food-grade products must comply with FDA requirements for food contact substances under Title 21 of the Code of Federal Regulations (21 CFR) and submit safety documentation; industrial-grade products are included in the Toxic Substances Control Act (TSCA) inventory, and importers must provide a TSCA compliance statement. Violations may result in cargo detention and fines of up to 2 million US dollars.
In the Asian market, China classifies it in the “Catalogue of Hazardous Chemicals” (2015 edition) and implements a safety production licensing system for manufacturers; Japan strictly regulates food raw materials through the Food Sanitation Act, requiring suppliers to provide complete production process traceability reports. Additionally, the transportation of this compound in international trade must comply with the International Maritime Dangerous Goods (IMDG) Code, requiring packaging and labeling as Class 3 flammable liquids.
Environmentally, the global trend toward green chemistry is driving production process upgrades. The emission of aldehyde byproducts in traditional production processes has become a regulatory focus.
Future Outlook
The market prospect of Ethyl 2-methyl-3,4-pentadienoate (CAS: 60523-21-9) is closely tied to the development of the food flavor, pharmaceutical R&D, and functional materials industries. Global consumption upgrading and industrial green transformation will serve as core drivers of market growth, with the global market size expected to maintain a compound annual growth rate (CAGR) of 6.5%-7.5% over the next five years.
On the demand side, three key growth drivers are evident:
The high-end development of the global food industry, where the expansion of natural-identical flavor demand will continue to drive consumption of high-purity products, particularly in the prepared food sector of emerging markets;
Increased R&D investment in the biopharmaceutical field, where the advancement of new anti-inflammatory and anti-tumor drug pipelines will enhance the demand elasticity of pharmaceutical-grade intermediates;
The expansion of applications in the functional materials sector, where the development of new energy vehicles and high-end construction industries will open up new growth space for industrial-grade products.
However, the market also faces multiple challenges:
Raw material price volatility risks: Isoprene, a key production raw material, is significantly affected by international oil prices, with price fluctuations of 20%-30%, increasing the difficulty of enterprise cost control;
Rising compliance costs: Tightening chemical regulatory policies worldwide (e.g., updates to the EU REACH Regulation) will pressure small and medium-sized suppliers;
High technical barriers: The complex production process and substantial R&D investment for high-purity products make it difficult for new entrants to achieve rapid breakthroughs.
In summary, Ethyl 2-methyl-3,4-pentadienoate (CAS: 60523-21-9) plays an irreplaceable strategic role as a key intermediate in the fine chemical industry, particularly in food flavors and pharmaceutical chemicals. Driven by downstream consumption upgrading, global market demand shows a steady growth trend. Despite challenges such as raw material price volatility and rising compliance costs, the overall market prospect remains positive with the green upgrading of production technologies and continuous expansion of application scenarios. In the future, market competition for this compound will focus on the comprehensive balance of quality, compliance, and cost. Enterprises with core technologies and global operation capabilities will lead the industry direction, serving as key links connecting basic chemicals and high-end consumer industries.
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3. Application Fields
As an important conjugated diene ester intermediate with a unique conjugated double bond structure, Ethyl 2-methyl-3,4-pentadienoate (CAS: 60523-21-9) has wide-ranging applications:
Chemical synthesis: Production of functional polymer monomers and conjugated polymers; acting as an active monomer in copolymerization reactions to enhance material performance;
Pharmaceutical intermediates: Key structural fragment for synthesizing certain anti-inflammatory drugs, antiviral drugs, and bioactive molecules;
New materials: Synthesis of high-performance coating film-forming agents, UV-curable resin reactive diluents, and rubber modifiers.
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Post time: Nov-27-2025