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[3-(4-BROMO-PHENYL)-ISOXAZOL-5-YL]-METHANOL(CAS#206055-91-6)

Chemical Property:

Molecular Formula C10H8BrNO2
Molar Mass 254.08
Storage Condition 2-8°C

Product Detail

Product Tags

Hazard Symbols Xn - Harmful
Risk Codes 22 - Harmful if swallowed
WGK Germany 3

 

Introduction

3-(4-BROMOPHENYL)-ISOXAZOL-5-METHANOL ([3-(4-BROMO-PHENYL)-ISOXAZOL-5-YL]-METHANOL) is an organic compound. The following is an introduction to its properties, uses, manufacturing methods, and safety information:Properties: [3-(4-bromophenyl)-isoxazole-5-yl]-methanol is a white solid crystal. It has medium solubility and is soluble in organic solvents such as methanol, ethanol and dimethyl ether at room temperature. It is a structure with bromobenzene rings and isoxazole rings.With its structural characteristics of the isoxazole ring and bromophenyl group, it may exhibit antibacterial and anti-inflammatory activities.Method: [3-(4-bromophenyl)-isoxazole-5-yl]-methanol can be synthesized by a variety of methods. A commonly used preparation method is to react bromophenyl with isoxazole functional compounds.Safety Information: Compounds vary in their specific applications and uses, and there may be some safety risks and precautions. In general, chemical laboratory operations should follow good laboratory safety protocols and wear appropriate personal protective equipment. When using or handling the compound, contact with the skin, eyes, and respiratory tract should be avoided to prevent harm to the human body. For specific safety precautions and toxicity information, reference is made to the compound's Material Safety Data Sheet (MSDS) or other reliable source of chemical safety information.

Application

[3-(4-Bromophenyl)isoxazol-5-yl]methanol (CAS 206055-91-6) is a versatile isoxazole-based building block featuring a reactive primary alcohol and a bromophenyl group. The bromine enables efficient cross-coupling reactions (Suzuki-Miyaura, Buchwald-Hartwig, Sonogashira), while the hydroxymethyl group allows oxidation, esterification, or ether formation, enabling rapid diversification for structure-activity relationship (SAR) studies. This compound serves as a key intermediate in medicinal chemistry for the synthesis of potent kinase inhibitors targeting cancer, inflammation, and neurological disorders. Its isoxazole core is a privileged scaffold found in numerous bioactive molecules, including anticancer, anti-inflammatory, and antimicrobial agents. Researchers also utilize this intermediate to develop selective modulators of GPCRs and other therapeutic targets. In agrochemical research, it contributes to the design of novel herbicides and fungicides. High purity ensures reproducible results in high-throughput screening and scalable GMP synthesis. Xinchem offers reliable custom synthesis, custom chemical synthesis, and contract manufacturing of this essential building block with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and global supply.


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