3,4-Dimethoxy-3-cyclobutene-1,2-dione(CAS#5222-73-1)
| Risk Codes | 42/43 – May cause sensitization by inhalation and skin contact. |
| Safety Description | S22 – Do not breathe dust. S24/25 – Avoid contact with skin and eyes. S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection. |
| WGK Germany | 3 |
| HS Code | 29145090 |
Introduction
3,4-Dimethoxy-3-cyclobutene-1,2-dione is an organic compound. Below is an introduction to its properties, uses, synthesis, and safety information:Properties:- 3,4-Dimethoxy-3-cyclobutene-1,2-dione is a solid compound that appears as colorless to pale yellow crystals.- The compound is stable at room temperature but can decompose under high temperatures or in the presence of strong acids.Uses:- 3,4-Dimethoxy-3-cyclobutene-1,2-dione has certain applications in organic synthesis.- It is commonly used as a reagent and raw material for synthesizing other compounds.- This compound can serve as an intermediate in the synthesis of curcuminoid compounds and other natural products.Synthesis:- 3,4-Dimethoxy-3-cyclobutene-1,2-dione can be synthesized through a chemical synthesis route.- One method involves dissolving cyclobutene-1,2-dione in dimethyl sulfoxide, then adding excess hydrobromic acid and methanol to initiate an acid-catalyzed nucleophilic addition reaction.- This reaction is typically carried out at low temperatures to avoid forming undesired by-products.Safety Information:- Data on the toxicity and hazards of 3,4-Dimethoxy-3-cyclobutene-1,2-dione is relatively limited.- As an organic compound, it should be handled with standard safety precautions, avoiding contact with skin and eyes.- Good ventilation should be ensured when using or handling the compound to avoid inhaling vapors or dust.- Hands should be thoroughly washed after handling. If necessary, appropriate personal protective equipment such as gloves and safety goggles should be worn.







