Methyl 2-benzoylbenzoate(CAS#606-28-0)
| Hazard Symbols | N - Dangerous for the environment |
| Risk Codes | 50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
| Safety Description | S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
| UN IDs | UN 3077 9/PG 3 |
| WGK Germany | 3 |
| HS Code | 29183000 |
Introduction
Methyl phthaloylbenzoate. Properties: Methyl phthaloylbenzoate is a colorless to pale yellow liquid with an aroma. It is soluble in ether, chloroform, ethanol and ether solvents and almost insoluble in water. Uses: Methyl phthaloylbenzoate has a wide range of applications in the chemical industry. It can also be used as an additive in coatings, inks, and plastics. Preparation method: The preparation of methyl phthalate benzoate is usually obtained by the condensation reaction of methyl benzoate and phenol. The specific step is to condense methyl benzoate and phenol under acidic conditions to obtain methyl phthaloylbenzoate. Safety information: Methyl phthaloylbenzoate is an organic compound, and it is necessary to pay attention to fire prevention and avoid contact with strong oxidizing agents during use and storage. Contact with the skin and inhalation of its vapors may cause irritation and damage to the human body, and appropriate protective equipment should be worn when operating. It should be used in a well-ventilated area and avoid prolonged contact.
Application
Methyl 2-benzoylbenzoate (CAS 606-28-0) is a key organic intermediate widely used in pharmaceutical and photopolymerization applications. It serves as a versatile building block for the synthesis of phenothiazine derivatives with antihistamine and central nervous system activity, and as an impurity standard for the API methylphenidate to support analytical method development and quality control. As a photoinitiator intermediate, it enables the production of benzophenone-type photoinitiators for UV-curable coatings, adhesives, and printing inks, where it absorbs UV light to initiate rapid radical polymerization, improving cure speed and surface properties. Additionally, its benzoylbenzoate scaffold undergoes cyclization and cross-coupling reactions to construct lactones and other heterocyclic frameworks used in medicinal chemistry. Xinchem offers custom synthesis and contract manufacturing of high-purity methyl 2-benzoylbenzoate with flexible scaling from R&D to commercial tons. Contact us for a competitive quote and reliable global supply.







