3-Hydroxybenzotrifluoride（CAS# 98-17-9)
| Risk Codes | R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes R34 - Causes burns R24/25 - R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| WGK Germany | 3 |
| RTECS | GP3510000 |
| TSCA | T |
| HS Code | 29081990 |
| Hazard Note | Irritant |
| Hazard Class | 8 |
Introduction
M-trifluoromethylphenol is an organic compound. The following is an introduction to its properties, uses, manufacturing methods and safety information:
Quality:
- Appearance: Colorless crystals or white crystalline powder
- Solubility: soluble in organic solvents such as ethanol, ether, chloroform, etc., slightly soluble in water.
Use:
- M-trifluoromethylphenol can be used as an intermediate in organic synthesis for the synthesis of other compounds.
Method:
- A common preparation method is to perform a hot nitrification reaction on toluene to obtain 3-nitromethylbenzene, and then replace one of the nitro groups with a fluorine atom by fluorination.
Safety Information:
- M-trifluoromethylphenol is an organic compound that is irritating and may cause irritation to the eyes, skin, and respiratory tract.
- Wear appropriate protective equipment, such as lab gloves, goggles, and protective masks, during handling or handling.
- Avoid violent reactions with strong oxidants, strong acids, strong alkalis, etc., to prevent dangerous situations.
- Pay attention to ventilation during use and avoid inhaling vapors or dust from the compound.
Application
3-Hydroxybenzotrifluoride (3-Trifluoromethylphenol, CAS 98-17-9) is a versatile fluorinated building block used extensively in pharmaceutical, agrochemical, and specialty chemical research. In pharmaceutical development, it serves as a key intermediate in the synthesis of the antiglaucoma agent Travoprost, as well as various antidepressants, antifungal agents, and anti-inflammatory drugs. In agrochemical research, this compound is a crucial precursor for the formulation of herbicides, pesticides, and insecticides with enhanced metabolic stability. It also acts as a building block in polymer chemistry for creating high-performance specialty polymers and materials. Furthermore, it is utilized as a reagent in analytical chemistry and in the production of electronic components. Its trifluoromethyl group imparts increased lipophilicity and metabolic stability to target molecules, making it an essential intermediate for custom synthesis and drug discovery programs. Xinchem offers high-purity 3-Hydroxybenzotrifluoride with flexible custom chemical synthesis and contract manufacturing to meet your research and production needs. Contact us for a competitive quote and reliable global supply.
