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The Essential Fluorinated Nitroaromatic Building Block for Enzalutamide, Apalutamide, and Advanced Pharmaceutical Intermediates: 2-Fluoro-4-nitrobenzoic Acid (CAS# 403-24-7)
2-Fluoro-4-nitrobenzoic acid (CAS# 403-24-7), also known as 4-carboxy-3-fluoronitrobenzene or 4-nitro-2-fluorobenzoic acid, is a fluorinated nitroaromatic carboxylic acid with the molecular formula C₇H₄FNO₄ and a molecular weight of 185.11 g/mol. Its molecular structure features a benzoic acid co...Read more -
The Pre-Functionalized 2-Aminothiazole Scaffold for Kinase Inhibitor Discovery, Metabolic Stability Optimization, and Late-Stage SAR Diversification: 5-Bromo-4-isopropylthiazol-2-amine (CAS# 102570...
5-Bromo-4-isopropylthiazol-2-amine (CAS# 1025700-49-5), also known as 2-amino-5-bromo-4-isopropylthiazole, 5-bromo-4-propan-2-yl-1,3-thiazol-2-amine, or 5-bromo-4-(1-methylethyl)-2-thiazolamine, is a functionalized heterocyclic building block with the molecular formula C₆H₉BrN₂S and a molecular w...Read more -
The Privileged Heterocyclic Primary Amine Building Block for GABA A Receptor Modulators, GSK3 Kinase Inhibitors, and HIV-1 Protease Inhibitors: 4-Aminoisoxazole (Isoxazol-4-amine, CAS# 108511-97-3)
4-Aminoisoxazole (CAS# 108511-97-3), also known as isoxazol-4-amine, 1,2-oxazol-4-amine, or isoxazole-4-amine, is a heterocyclic primary amine with the molecular formula C₃H₄N₂O and a molecular weight of 84.08 g/mol. Its molecular structure features a five-membered isoxazole ring bearing a primar...Read more -
The Chemoselective Bifunctional Alkylating Agent for Pentoxifylline Synthesis, Pharmaceutical Intermediates, and Specialty Agrochemicals: 6-Bromohexan-2-one (CAS# 10226-29-6)
6-Bromohexan-2-one (CAS# 10226-29-6), also known as 6-bromo-2-hexanone, 5-oxohexyl bromide, 1-bromo-5-hexanone, or 4-bromobutyl methyl ketone, is a C6 aliphatic bromoketone with the molecular formula C₆H₁₁BrO and a molecular weight of 179.05 g/mol. Its molecular structure combines a terminal prim...Read more -
The Regioselective Dibromo Arylacetic Acid Building Block for Elbasvir, HCV NS5A Inhibitors, and Antiviral Drug Development: 2,5-Dibromophenylacetic Acid (CAS# 203314-28-7)
2,5-Dibromophenylacetic acid (CAS# 203314-28-7), also known as 2-(2,5-dibromophenyl)acetic acid or benzeneacetic acid, 2,5-dibromo-, is a regioselectively dibrominated arylacetic acid with the molecular formula C₈H₆Br₂O₂ and a molecular weight of 293.94 g/mol. Its molecular structure consists of ...Read more -
The Regioselective 2H-Indazole Building Block and Essential Intermediate for Pazopanib and Angiokinase Inhibitor Therapeutics: 2,3-Dimethyl-2H-indazol-6-amine (CAS# 444731-72-0)
2,3-Dimethyl-2H-indazol-6-amine (CAS# 444731-72-0), also known as 6-amino-2,3-dimethyl-2H-indazole, 2,3-dimethyl-6-amino-2H-indazole, 2,3-dimethylindazol-6-amine, or Pazopanib Related Compound 5, is a regioselectively methylated indazole derivative with the molecular formula C₉H₁₁N₃ and a molecul...Read more -
The Isomer-Specific Fluorinated Building Block for Voriconazole, Fluconazole, and Fluoroquinolone Antibiotics: 2,4-Difluorobenzoic Acid (CAS# 1583-58-0)
2,4-Difluorobenzoic acid (CAS# 1583-58-0), also known as 2,4-difluorobenzenecarboxylic acid or 2,4-difluorophenylcarboxylic acid, is a fluorinated aromatic carboxylic acid with the molecular formula C₇H₄F₂O₂ and a molecular weight of 158.10 g/mol. Its molecular structure consists of a benzoic aci...Read more -
The Essential Precursor and Reference Standard for [¹⁸F]FET PET Brain Tumor Imaging and Neurological Drug Discovery: L-Tyrosine, O-(2-fluoroethyl)-, trifluoroacetate (CAS# 854750-33-7)
L-Tyrosine, O-(2-fluoroethyl)-, trifluoroacetate (CAS# 854750-33-7), also known as O-(2-fluoroethyl)-L-tyrosine trifluoroacetate, FET trifluoroacetate, or L-FET TFA, is a fluorinated chiral amino acid derivative with the molecular formula C₁₁H₁₄FNO₃·C₂HF₃O₂ and a molecular weight of 341.26 g/mol....Read more -
The Privileged 7-Azaindole Kinase Scaffold for FGFR Inhibitors, Antiviral Agents, and Precision Oncology: 1H-Pyrrolo[2,3-b]pyridine-4-carboxylic Acid (CAS# 479553-01-0)
1H-Pyrrolo[2,3-b]pyridine-4-carboxylic acid (CAS# 479553-01-0), also known as 7-azaindole-4-carboxylic acid or 7-azaindole-4-carboxylic acid, is a fused heterocyclic building block with the molecular formula C₈H₆N₂O₂ and a molecular weight of 162.15 g/mol. Its molecular structure features a 7-aza...Read more -
The Fluorinated Benzophenone Building Block for Pitavastatin, Fluorescent Probes, and Pharmaceutical Intermediates: 2-Amino-4′-fluorobenzophenone (CAS# 3800-06-4)
2-Amino-4′-fluorobenzophenone (CAS# 3800-06-4), also known as (2-aminophenyl)(4-fluorophenyl)methanone or 2-amino-4′-fluorodiphenylmethanone, is a fluorinated benzophenone derivative with the molecular formula C₁₃H₁₀FNO and a molecular weight of 215.22 g/mol. Its molecular structure c...Read more
