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5-Bromo-4-isopropylthiazol-2-amine (CAS# 1025700-49-5), also known as 2-amino-5-bromo-4-isopropylthiazole, 5-bromo-4-propan-2-yl-1,3-thiazol-2-amine, or 5-bromo-4-(1-methylethyl)-2-thiazolamine, is a functionalized heterocyclic building block with the molecular formula C₆H₉BrN₂S and a molecular weight of 221.12 g/mol. Its molecular structure features a five-membered 2-aminothiazole core bearing a bromine atom at the 5-position and an isopropyl group at the 4-position. This specific substitution pattern—a bromine handle at C5 for late-stage diversification combined with a sterically demanding isopropyl group at C4—confers a unique physicochemical and synthetic profile that distinguishes 5-bromo-4-isopropylthiazol-2-amine from its close structural analogs, making it an indispensable tool in modern kinase inhibitor discovery and medicinal chemistry.

The compound is a solid at room temperature (typically appearing as a white to off-white crystalline powder or liquid), with a predicted density of 1.571 ± 0.06 g/cm³, a predicted boiling point of 303.1 ± 22.0°C at 760 mmHg, a predicted flash point of 137.1 ± 22.3°C, and a predicted pKa of 4.66 ± 0.10. Its calculated LogP of 3.19 provides favorable lipophilicity for membrane permeability, while the topological polar surface area of 67.2 Å² is consistent with good oral bioavailability potential. The compound is soluble in organic solvents such as ethanol, dimethyl sulfoxide, and chloroform. It is typically supplied at ≥96% purity (GC/HPLC) and should be stored under refrigeration (2–8°C) in a tightly sealed container protected from light and moisture. Under GHS, it is classified with the signal word “Warning” (H302, H315, H319, H335) and requires standard laboratory safety precautions during handling.

5-Bromo-4-isopropylthiazol-2-amine is a strategically important pre-functionalized 2-aminothiazole scaffold that serves as a versatile synthetic intermediate for the development of potent kinase inhibitors targeting cancer, inflammation, and autoimmune diseases, as well as a valuable building block for antiviral, antibacterial, and antifungal agents. The 2-aminothiazole core is a privileged structure in medicinal chemistry, appearing in numerous approved drugs and clinical candidates. The compound’s unique combination of a reactive bromine handle at C5, a free amino group at C2, and a metabolically stabilizing isopropyl group at C4 enables efficient late-stage diversification for structure-activity relationship (SAR) studies, making it an essential building block for medicinal chemists seeking to accelerate lead optimization. Based on its chemical characteristics and industrial significance, this article systematically analyzes the key properties, core application areas, global market structure, regulatory landscape, and future outlook of this strategically important functionalized aminothiazole building block.

Core Application Fields and Demand

Market demand for 5-bromo-4-isopropylthiazol-2-amine (CAS# 1025700-49-5) is concentrated in three primary sectors: pharmaceutical R&D and kinase inhibitor discovery (approximately 55–60% of global consumption), medicinal chemistry and chemical probe development (approximately 25–30%), and specialty chemical synthesis and agrochemical development (approximately 10–15%). Its pre-functionalized 2-aminothiazole scaffold and late-stage diversification capability serve as the core drivers of sustained demand growth.

In pharmaceutical R&D and kinase inhibitor discovery, 5-bromo-4-isopropylthiazol-2-amine addresses a critical bottleneck in medicinal chemistry: researchers optimizing kinase inhibitor leads often face lengthy de novo synthesis of analogs. This compound provides a pre-functionalized 2-aminothiazole scaffold that enables rapid late-stage diversification. The 2-aminothiazole core is a well-recognized scaffold for developing potent kinase inhibitors, and the isopropyl group at the 4-position is a critical pharmacophore for achieving high potency. The compound has been specifically cited in the development of Checkpoint Kinase 1 (CHK1) inhibitors as novel anticancer agents, as well as in the synthesis of EIF4E inhibitors for cancer therapy. It serves as a key intermediate for the synthesis of kinase inhibitors targeting JAK, BTK, CDK, and PI3K pathways, which are implicated in cancer, inflammation, and autoimmune diseases. The bromine at the 5-position enables efficient palladium-catalyzed cross-coupling reactions (Suzuki-Miyaura, Buchwald-Hartwig, Sonogashira) to introduce diverse aryl, heteroaryl, or alkyl substituents for SAR exploration.

In medicinal chemistry and chemical probe development, 5-bromo-4-isopropylthiazol-2-amine serves as a versatile building block for constructing focused libraries of bioactive molecules. The free amino group at C2 allows acylation, alkylation, and urea formation, while the bromine handle enables late-stage functionalization. The isopropyl group at the 4-position provides steric bulk for metabolic stability and pharmacophore optimization. The compound is used as a biochemical probe to study thiazole-related biological pathways, and its rigid thiazole core offers excellent target binding affinity and pharmacokinetic properties. High-purity material ensures reproducible results in high-throughput screening, SAR studies, and scalable GMP manufacturing.

In specialty chemical synthesis and agrochemical development, 5-bromo-4-isopropylthiazol-2-amine is employed as a key intermediate for the synthesis of agrochemical active ingredients. The 2-aminothiazole scaffold is a common structural motif in modern crop protection agents, and the compound’s derivatives are explored for their potential in developing novel fungicides, herbicides, and insecticides. The compound is also used as a reference material for analytical method development and quality control in the pharmaceutical and agrochemical industries.

Key Properties and Reactivity Profile

5-Bromo-4-isopropylthiazol-2-amine (CAS# 1025700-49-5) is a pre-functionalized 2-aminothiazole whose value derives from the orthogonal reactivity of its bromine, amino, and isopropyl substituents.

Key physicochemical parameters include:

Molecular Formula: C₆H₉BrN₂S
Molecular Weight: 221.12 g/mol
CAS Number: 1025700-49-5
MDL Number: MFCD09834790
Synonyms: 2-Amino-5-bromo-4-isopropylthiazole; 5-Bromo-4-propan-2-yl-1,3-thiazol-2-amine; 5-Bromo-4-(1-methylethyl)-2-thiazolamine
IUPAC Name: 5-bromo-4-propan-2-yl-1,3-thiazol-2-amine
Appearance: White to off-white solid or crystalline powder
Purity: ≥96% (GC/HPLC); ≥98% available
Predicted Density: 1.571 ± 0.06 g/cm³
Predicted Boiling Point: 303.1 ± 22.0°C at 760 mmHg
Predicted Flash Point: 137.1 ± 22.3°C
Predicted pKa: 4.66 ± 0.10
Calculated LogP: 3.19 (XLogP3); 2.8 (ACD/LogP)
Topological Polar Surface Area: 67.2 Å²
Hydrogen Bond Acceptor Count: 3
Hydrogen Bond Donor Count: 1
Rotatable Bond Count: 1
SMILES: CC(C)C1=C(SC(=N1)N)Br
InChIKey: PLPKYAYJIVQOEL-UHFFFAOYSA-N
Solubility: Soluble in ethanol, dimethyl sulfoxide, chloroform
Storage: 2–8°C, sealed, protect from light and moisture
GHS Classification: Warning; H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), H335 (May cause respiratory irritation)
Hazard Symbols: GHS07 – Harmful/Irritant
HS Code: 29341000 (heterocyclic compounds containing a thiazole ring)

The compound’s reactivity is defined by its three orthogonal handles: the bromine atom at C5 serves as the preferential site for palladium-catalyzed cross-coupling reactions (Suzuki-Miyaura, Buchwald-Hartwig, Sonogashira), enabling the introduction of diverse aryl, heteroaryl, and alkyl substituents; the free amino group at C2 enables acylation, alkylation, sulfonylation, and urea formation; and the isopropyl group at C4 provides steric and lipophilic modulation. The specific combination of the 5-bromo and 4-isopropyl substituents on the 2-aminothiazole core confers a unique profile of physicochemical properties and synthetic utility. Substituting it with compounds bearing different alkyl groups (e.g., 4-methyl) or lacking the halogen (e.g., 4-isopropylthiazol-2-amine) can significantly alter lipophilicity (LogP), molecular weight, and metabolic stability, thereby impacting lead optimization outcomes. The isopropyl group is a critical pharmacophore for achieving high potency and cannot be assumed to be interchangeable with smaller alkyl chains without experimental validation.

Major Market Participants

The global supply system for 5-bromo-4-isopropylthiazol-2-amine (CAS# 1025700-49-5) features a pattern of “specialized heterocyclic building block manufacturers, multinational research chemical distributors, and Chinese producers serving distinct market segments.” As a specialized pre-functionalized aminothiazole scaffold rather than a bulk commodity, the market is characterized by a moderate number of suppliers catering to pharmaceutical R&D, medicinal chemistry, and academic research.

In the global research and high-purity segment, key international suppliers include Fluorochem (UK), offering the compound at 98% purity under product code F092624, with packaging sizes from 250 mg (£13.00) to 25 g (£458.00) and in-stock availability in the UK and Europe. AK Scientific (AKSci) offers the compound at 96% purity under product code X8620, with pricing from $46.00 for 1 g to $841.00 for 25 g, shipped from the SF Bay Area, California. BOC Sciences offers 2-amino-5-bromo-4-isopropylthiazole as a useful research chemical with over 20,000 building blocks and intermediates from stock, process scale-up from lab to industrial scale, and flexible batch sizes. BenchChem offers the compound at ≥96% purity under catalog number B1442367, emphasizing its role as a pre-functionalized 2-aminothiazole scaffold for kinase inhibitor lead optimization, with the C5 bromo handle enabling rapid late-stage diversification for SAR studies. Aladdin Scientific offers the compound at 96% purity under product code A178854, with 1 g and 5 g packaging options. GlpBio offers the compound as a master of small molecules. Smolecule offers the compound as a research chemical for pharmaceutical development and biological research. CymitQuimica (Fluorochem/Indagoo brand) offers the compound at 98% purity with pricing from €23.00 to €605.00. ChemScene offers the compound at 98% purity under catalog number CS-0003922. Ambeed offers the compound under catalog number A123893. Hoffman Chemicals offers the compound with a price of $1,239.00. These suppliers serve the pharmaceutical, biotechnology, and academic research communities with products that meet rigorous quality specifications.

In the industrial and large-scale production segment, Chinese manufacturers have emerged as significant players in the global supply chain. XinChem is a reliable manufacturer and supplier of high-purity 5-bromo-4-isopropylthiazol-2-amine from China, offering the compound with stringent quality standards for use in kinase inhibitor discovery, medicinal chemistry, and bioactive molecule synthesis. XinChem provides the compound as a white to off-white solid with comprehensive quality documentation, batch-specific Certificates of Analysis (COA), customizable packaging, and globally compliant REACH, ISO 9001, and GMP-aligned manufacturing. The company emphasizes that the bromine at the 5-position enables efficient palladium-catalyzed cross-coupling reactions, while the free amino group allows acylation, alkylation, or urea formation, and the isopropyl group at the 4-position provides steric and lipophilic modulation, enhancing metabolic stability and target selectivity. XinChem offers custom synthesis, custom chemical synthesis, and contract manufacturing of this essential building block with flexible scaling from R&D to commercial tons. Other Chinese suppliers include Bide Pharmatech (毕得医药), offering the compound at 96% purity under catalog number BD104632 with batch quality inspection reports (NMR, HPLC, GC). Beyotime Biotechnology (碧云天) offers the compound at 96% purity under product code Y159444, with packaging sizes of 200 mg (¥73.00), 1 g (¥290.00), and 5 g (¥1,157.00). J&K Scientific (百灵威) offers the compound at 98% purity under product code F092624. MolCore (摩库) offers the compound at NLT 98% purity, compliant with ISO certification systems. Alfa Chemistry offers the compound at 97% purity under product code 1025700-49-5. Capot Chemical offers the compound with kilogram-scale production and long-term commercial supply support. Shanghai Aladdin Biochemical Technology offers the compound under catalog number A178854. Chinese suppliers offer the compound at various purity grades (typically 96–98%) and packaging options—from grams to multi-kilogram quantities—serving both domestic and export markets.

Regional Market Dynamics

The global 5-bromo-4-isopropylthiazol-2-amine market exhibits distinct regional characteristics, with production concentrated in Asia-Pacific (particularly China) and consumption distributed across North America, Europe, and the Asia-Pacific region, aligned with the pharmaceutical, biotechnology, and academic research industries in these regions.

The Asia-Pacific region has emerged as a significant production hub for 5-bromo-4-isopropylthiazol-2-amine, with China hosting numerous manufacturers and suppliers including XinChem. The region’s competitive advantages include lower production costs, established chemical infrastructure, and proximity to rapidly growing pharmaceutical and biotechnology industries. Chinese suppliers offer the compound at various purity grades (typically 96–98%) and packaging options, serving both domestic and export markets. The growing pharmaceutical R&D, kinase inhibitor discovery, and medicinal chemistry sectors in China, India, Japan, and South Korea continue to drive regional consumption growth. The compound is classified as a pharmaceutical intermediate and organic synthesis intermediate in the Chinese market, with multiple suppliers offering the product in packaging sizes ranging from 200 mg to 25 g.

North America remains a key market for high-purity and research-grade 5-bromo-4-isopropylthiazol-2-amine, driven by demand from the pharmaceutical industry, biotechnology companies, and academic research institutions. The United States hosts numerous research organizations, pharmaceutical companies, and contract research organizations that require high-quality pre-functionalized aminothiazole scaffolds for kinase inhibitor discovery and medicinal chemistry programs. AK Scientific, BOC Sciences, BenchChem, and GlpBio serve the North American market with extensive distribution networks. The region’s well-established regulatory framework, including FDA oversight of pharmaceutical R&D, supports demand for high-grade research chemicals and pharmaceutical intermediates.

Europe is characterized by stringent regulatory requirements, including REACH registration, and a strong focus on quality and sustainability in pharmaceutical and chemical research. European pharmaceutical companies, medicinal chemistry laboratories, and research institutions demand high-purity heterocyclic building blocks with comprehensive documentation. Fluorochem (UK) and CymitQuimica serve the European market with in-stock availability. The compound is registered under REACH with MDL number MFCD09834790.

Japan represents a specialized market where 5-bromo-4-isopropylthiazol-2-amine is supplied by Fujifilm Wako Pure Chemical and other distributors for pharmaceutical research, kinase inhibitor development, and fine chemical applications.

Regulatory and Safety Considerations

As a halogenated heterocyclic amine and pharmaceutical intermediate, 5-bromo-4-isopropylthiazol-2-amine (CAS# 1025700-49-5) is subject to regulatory oversight in major global economies. Compliance with relevant regulations is essential for market access and trade.

GHS classification and handling: 5-Bromo-4-isopropylthiazol-2-amine is classified with the signal word “Warning”. Hazard statements include H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). The compound is classified as Acute Tox. 4 (Oral) , Skin Irrit. 2, Eye Irrit. 2, and STOT SE 3 (respiratory system). Precautionary statements include P101 (If medical advice is needed, have product container or label at hand), P260 (Do not breathe dust/fume/gas/mist/vapours/spray), P264 (Wash hands thoroughly after handling), P270 (Do not eat, drink or smoke when using this product), P271 (Use only outdoors or in a well-ventilated area), P280 (Wear protective gloves/protective clothing and eye/face protection), P301+P310 (IF SWALLOWED: Immediately call a POISON CENTER/doctor), P301+P330+P331 (IF SWALLOWED: Rinse mouth. Do NOT induce vomiting), P303+P361+P353 (IF ON SKIN: Take off immediately all contaminated clothing; rinse skin with water), P304+P340 (IF INHALED: Remove person to fresh air and keep comfortable for breathing), and P305+P351+P338 (IF IN EYES: Rinse cautiously with water for several minutes; remove contact lenses if present and easy to do; continue rinsing). The compound is classified as GHS07 – Harmful/Irritant. Personal protective equipment including lab gloves, safety glasses, and a lab coat should be worn during handling, and operations should be conducted in a well-ventilated environment or fume hood.

Storage and stability: 5-Bromo-4-isopropylthiazol-2-amine should be stored at 2–8°C in a tightly sealed container protected from light and moisture. The compound is stable under recommended storage conditions but should be kept away from strong oxidizing agents and bases.

Regulatory compliance: In the European Union, the compound must comply with REACH registration requirements for import and use. The compound has an MDL number of MFCD09834790. Manufacturers and suppliers must provide comprehensive Safety Data Sheets (SDS) and maintain appropriate documentation. In the United States, 5-bromo-4-isopropylthiazol-2-amine is intended for research and development use only and is not intended for therapeutic, food, cosmetic, or consumer applications unless explicitly stated otherwise. For pharmaceutical intermediate applications, manufacturers must comply with relevant FDA regulations and quality standards. The compound is not a controlled substance.

Transport information: 5-Bromo-4-isopropylthiazol-2-amine is not classified as hazardous material for DOT/IATA transport purposes under standard conditions. Proper packaging, labeling, and documentation are nevertheless required for international shipping. The HS code for the compound is 29341000 (heterocyclic compounds containing a thiazole ring). The compound is typically shipped at ambient temperature with appropriate protection from light and moisture.

Future Outlook

The market outlook for 5-bromo-4-isopropylthiazol-2-amine is positive, supported by several key growth drivers across its major application segments. While the compound remains a relatively specialized pre-functionalized aminothiazole scaffold, its essential role in kinase inhibitor discovery and its utility in late-stage SAR diversification position it for steady growth in the coming years.

Key growth drivers include:

Expansion of kinase inhibitor R&D: The continued development of kinase inhibitors for oncology, inflammation, and autoimmune diseases drives demand for pre-functionalized 2-aminothiazole scaffolds that enable rapid late-stage diversification. The compound’s demonstrated utility in CHK1 inhibitor and EIF4E inhibitor development supports sustained demand from oncology drug discovery programs.
Growth in medicinal chemistry and SAR studies: The increasing emphasis on accelerating lead optimization and SAR exploration drives demand for building blocks that enable efficient late-stage functionalization. The compound’s C5 bromo handle and C2 amino group provide orthogonal reactivity for rapid analog synthesis.
Increasing focus on metabolic stability optimization: The isopropyl group at the 4-position is a critical pharmacophore for achieving high potency and metabolic stability. As drug discovery programs increasingly prioritize metabolic stability, demand for the 4-isopropyl-substituted scaffold grows.
Expansion of pharmaceutical R&D in Asia: The growth of pharmaceutical R&D and API manufacturing in China and India—driven by increasing investment in generic drug production and innovative drug discovery—supports demand for high-quality heterocyclic building blocks and pharmaceutical intermediates.
Growth in chemical probe and biochemical research: The compound’s utility as a biochemical probe for studying thiazole-related biological pathways supports demand from academic and industrial research laboratories.

Challenges and considerations:

Limited scale: As a specialized pre-functionalized aminothiazole scaffold, the market for 5-bromo-4-isopropylthiazol-2-amine is smaller than that of commodity chemicals.
Competition from alternative building blocks: The market faces competition from other 2-aminothiazole derivatives and heterocyclic building blocks with similar reactivity profiles.
Handling requirements: The compound’s classification as an irritant (H302, H315, H319, H335) requires appropriate safety measures during handling and storage.
Regulatory compliance: Increasingly stringent pharmaceutical and chemical regulations may require ongoing investment in quality systems and documentation.

To succeed in this evolving market landscape, suppliers must focus on product quality (particularly purity and batch-to-batch consistency), supply chain reliability, regulatory compliance, and responsive customer service. Companies that can offer high-purity products, flexible packaging options, and technical support for pharmaceutical, medicinal chemistry, and drug discovery applications will be well-positioned to capture growing demand.

Shanghai XinChem Co., Ltd. (XinChem)

As a world-leading supplier of organic chemicals and heterocyclic building blocks, Shanghai XinChem Co., Ltd. (XinChem) is dedicated to meeting the innovative needs of the pharmaceutical, biotechnology, and fine chemical industries. Leveraging extensive experience and advanced manufacturing capabilities, XinChem provides high-quality 5-Bromo-4-isopropylthiazol-2-amine (CAS# 1025700-49-5) to customers worldwide. As a trusted manufacturer and supplier based in China, XinChem combines competitive pricing, reliable supply, and exceptional service to establish itself as a preferred partner for pharmaceutical companies, medicinal chemistry researchers, and drug discovery institutions seeking this versatile pre-functionalized 2-aminothiazole building block.

1. Technical Advantages

Advanced Synthesis and Purification Processes
XinChem utilizes state-of-the-art manufacturing facilities and rigorous quality control measures to ensure the purity, consistency, and safety of its 5-bromo-4-isopropylthiazol-2-amine products. The production process incorporates established synthetic routes—including the reaction of propylthiophenol and 2-bromoacetonitrile in the presence of a base, followed by cyclization and purification—enabling the delivery of products with purity ≥96% (GC/HPLC) and ≥98% (GC/HPLC) to meet diverse application requirements. Strict process control ensures consistent product quality, minimal impurities, and batch-to-batch reproducibility, providing customers with reliable performance in kinase inhibitor discovery, medicinal chemistry, and bioactive molecule synthesis.

Full-Chain Quality Control
The production process strictly adheres to international quality standards, with comprehensive quality control covering raw material sourcing, in-process monitoring, and finished product testing. Each batch is accompanied by a detailed Certificate of Analysis (COA) documenting physical and chemical properties, purity data (GC/HPLC), and impurity profiles. XinChem offers batch-specific COA, customizable packaging, and globally compliant REACH, ISO 9001, and GMP-aligned manufacturing.

2. Product Advantages

High Purity and Consistent Quality
XinChem offers 5-bromo-4-isopropylthiazol-2-amine with purity ≥96% (GC/HPLC) and ≥98% (GC/HPLC) available, ensuring optimal performance in kinase inhibitor discovery, medicinal chemistry, and bioactive molecule synthesis. The product’s high purity minimizes the risk of unwanted side reactions and impurities, making it suitable for demanding applications in drug discovery, SAR studies, and chemical probe development. The compound is supplied as a white to off-white solid with consistent appearance and defined physicochemical properties.

Comprehensive Specifications
Key specifications include:

Molecular Formula: C₆H₉BrN₂S
Molecular Weight: 221.12 g/mol
CAS Number: 1025700-49-5
MDL Number: MFCD09834790
Synonyms: 2-Amino-5-bromo-4-isopropylthiazole; 5-Bromo-4-propan-2-yl-1,3-thiazol-2-amine; 5-Bromo-4-(1-methylethyl)-2-thiazolamine
Appearance: White to off-white solid or crystalline powder
Purity: ≥96% (GC/HPLC) / ≥98% (GC/HPLC) available
Predicted Density: 1.571 ± 0.06 g/cm³
Predicted Boiling Point: 303.1 ± 22.0°C at 760 mmHg
Predicted Flash Point: 137.1 ± 22.3°C
Predicted pKa: 4.66 ± 0.10
Calculated LogP: 3.19 (XLogP3)
Topological Polar Surface Area: 67.2 Å²
Solubility: Soluble in ethanol, dimethyl sulfoxide, chloroform
Storage: 2–8°C, sealed, protect from light and moisture
GHS Classification: Warning; H302, H315, H319, H335
HS Code: 29341000

Flexible Packaging Solutions
XinChem provides a range of packaging options to accommodate diverse customer needs, from laboratory-scale quantities (250 mg, 1 g, 5 g) to industrial-scale packaging (10 g, 25 g, 100 g, 500 g, 1 kg) and bulk shipments. Customized packaging solutions are available upon request, ensuring safe handling, storage, and transportation with appropriate protection from light and moisture.

3. Application Fields

As a pre-functionalized 2-aminothiazole scaffold, 5-Bromo-4-isopropylthiazol-2-amine (CAS# 1025700-49-5) exhibits wide application value across multiple industries:

Pharmaceutical R&D and Kinase Inhibitor Discovery:

Pre-functionalized 2-aminothiazole scaffold for kinase inhibitor lead optimization
Key intermediate for Checkpoint Kinase 1 (CHK1) inhibitors as novel anticancer agents
Building block for EIF4E inhibitors for cancer therapy
Precursor for kinase inhibitors targeting JAK, BTK, CDK, and PI3K pathways
Enables rapid late-stage diversification via C5 bromo handle for SAR studies

Medicinal Chemistry and Chemical Probe Development:

Versatile building block for constructing focused libraries of bioactive molecules
C2 amino group enables acylation, alkylation, and urea formation
C5 bromo handle enables Suzuki-Miyaura, Buchwald-Hartwig, and Sonogashira coupling
4-Isopropyl group provides steric bulk for metabolic stability and pharmacophore optimization
Biochemical probe for studying thiazole-related biological pathways

Specialty Chemical Synthesis and Agrochemical Development:

Key intermediate for agrochemical active ingredients
Building block for novel fungicides, herbicides, and insecticides
Reference material for analytical method development and quality control

4. Service Support

Technical Expertise and Customized Solutions
XinChem’s team of experienced chemists and application engineers provides full technical support throughout the customer journey—from product selection and specification development to application guidance and troubleshooting. Whether customers require optimization of cross-coupling reaction conditions, guidance on late-stage diversification strategies, or assistance with regulatory documentation, XinChem’s technical experts are ready to help. Custom synthesis and contract manufacturing with flexible scaling from R&D to commercial tons are available upon request.

Global Logistics and Reliable Supply
With established supply chains serving markets across Europe, North America, Asia-Pacific, and beyond, XinChem ensures timely delivery and consistent product availability. The company’s logistics team manages all aspects of international shipping, including customs clearance and documentation, with appropriate temperature control (2–8°C) and moisture protection for product stability.

Regulatory Support
XinChem provides comprehensive documentation to support regulatory compliance, including Safety Data Sheets (SDS), Certificates of Analysis (COA), and other required certificates. The company stays current with evolving regulatory requirements in major markets, including REACH, TSCA, and other regional regulations, helping customers navigate the complexities of global trade.

5. Reasons to Choose XinChem

Professionalism: Extensive experience and deep expertise in heterocyclic building block synthesis and supply.
Quality: Rigorous quality control, high purity (≥96% to ≥98%), and adherence to international standards.
Reliability: Stable supply, competitive pricing, and timely delivery.
Flexibility: Customized solutions to meet diverse customer needs, including custom synthesis and packaging.
Service: Responsive technical support and comprehensive documentation including batch-specific COA.

Website: www.xinchem.com

Email: sales1@xinchem.com

WhatsApp: +86 18049800532

Post time: Oct-07-2026

The Pre-Functionalized 2-Aminothiazole Scaffold for Kinase Inhibitor Discovery, Metabolic Stability Optimization, and Late-Stage SAR Diversification: 5-Bromo-4-isopropylthiazol-2-amine (CAS# 1025700-49-5)