4-Phenylpyridine（CAS# 939-23-1)
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| RTECS | UT7141000 |
| FLUKA BRAND F CODES | 10 |
| HS Code | 29333990 |
| Hazard Class | IRRITANT, KEEP COLD |
Introduction
Insoluble in cold water, soluble in ethanol and ether
Application
4-Phenylpyridine (CAS 939-23-1) is a versatile heteroaromatic building block consisting of a pyridine ring substituted with a phenyl group at the 4-position. It serves as a key intermediate in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. In medicinal chemistry, it is used to develop NK-1 receptor antagonists and M1 muscarinic acetylcholine receptor positive allosteric modulators (PAMs). As a ligand, it forms stable metal complexes for catalysis and coordination chemistry. In organic synthesis, 4-phenylpyridine participates in Heck coupling and acts as a pyridine catalyst for borylation reactions. It is also a precursor to the herbicide Cyperquat (1-methyl-4-phenylpyridinium). Xinchem offers high-purity 4-phenylpyridine with flexible custom synthesis and contract manufacturing, supporting reliable scale-up from R&D to commercial tons. Contact us for a competitive quote and global supply.
