Malonaldehyde bis(diethyl acetal)(CAS#122-31-6)

Introduction

1,1,3,3-Tetraethoxypropane is an organic compound. The following is an introduction to its properties, uses, manufacturing methods and safety information:Quality:1,1,3,3-Tetraethoxypropane is a colorless to pale yellow liquid. It has a lower density and is less volatile. The compound is soluble in some organic solvents such as alcohols and ketones.Use:1,1,3,3-tetraethoxypropane is commonly used as an impregnating agent, combustion stabilizer and solvent. In chemical synthesis, it is commonly used in the synthesis of surfactants, catalysts, coatings, and resins.Method:1,1,3,3-Tetraethoxypropane can be obtained by the reaction of triformaldehyde and ethanol under alkaline conditions. The specific preparation method includes the reaction of triformaldehyde with ethanol to form ethanol acetal, and then reacts with ethanol in the presence of an alkaline catalyst to obtain the desired product.Safety Information:- The compound is irritating and contact with the skin and eyes should be avoided.- The compound needs to be handled in a well-ventilated area to avoid its vapor or dust build-up.- Use personal protective equipment such as safety glasses, gloves and protective clothing.- When this compound is heated or exposed to an open flame, it may produce toxic gases and should be avoided from contact with heat sources or open flames.- Avoid contact with oxidants and strong acids to prevent dangerous reactions.When applying 1,1,3,3-tetraethoxypropane, proper operating procedures should be followed, and the compound should be properly stored and handled.

Application
Malonaldehyde bis(diethyl acetal) (1,1,3,3-Tetraethoxypropane, CAS 122-31-6) is a stable, protected form of malonaldehyde (MDA), a highly reactive three-carbon dialdehyde widely used in organic synthesis. It serves as a key precursor for generating malonaldehyde in situ under mild acidic conditions, enabling efficient access to reactive intermediates. As a versatile building block, it is extensively employed in pharmaceutical research for the synthesis of heterocyclic compounds, including pyrimidines, pyrazoles, isoxazoles, and diazepines, many of which exhibit anticancer, antiviral, antibacterial, and anti-inflammatory activities. It is also used to prepare malonaldehyde-based fluorescent probes for biological imaging, covalent crosslinkers for protein and nucleic acid chemistry, and specialty dye intermediates. Additionally, it finds application in agrochemical development and as a reference standard for oxidative stress biomarker analysis. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of high-purity malonaldehyde bis(diethyl acetal) with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.