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3,4-Dihydro-2-methoxy-2H-pyran(CAS#4454-05-1)

Chemical Property:

Molecular Formula C6H10O2
Molar Mass 114.14
Density 1.006 g/mL at 25 °C(lit.)
Boling Point 126 °C
Flash Point 16 °C
Solubility soluble in Methanol
Vapor Presure 5.14mmHg at 25°C
Appearance Liquid
Color Clear colorless to yellow
BRN 107274
Storage Condition Inert atmosphere,Room Temperature
Refractive Index 1.441-1.443

Product Detail

Product Tags

Hazard Symbols Xn - HarmfulF,Xn -
Risk Codes R22 - Harmful if swallowed
R11 - Highly Flammable
R36 - Irritating to the eyes
R20 - Harmful by inhalation
R10 - Flammable
Safety Description S9 - Keep container in a well-ventilated place.
S33 - Take precautionary measures against static discharges.
S16 - Keep away from sources of ignition.
S36 - Wear suitable protective clothing.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
UN IDs 1993
RTECS UP7900000
TSCA Yes
HS Code 29329900
Hazard Class 3
Packing Group II

 

Introduction

3,4-Dihydro-2-methoxy-2H-pyran is an organic compound. It is a colorless liquid with a peculiar odor. The following is an introduction to some properties, uses, preparation methods and safety information about 3,4-dihydro-2-methoxy-2H-pyran:Quality:- Soluble in water and a variety of organic solvents- Has good stability, but is sensitive to strong oxidantsUse:3,4-Dihydro-2-methoxy-2H-pyran has a variety of applications in the chemical industry:- It is an important solvent that can be used in organic synthesis reactions such as hydrogenation, esterification, etc.Method:The preparation of pyranos is generally achieved by catalytic hydrogenation reactions. 3,4-Dihydro-2-methoxy-2H-pyran can be obtained by hydrogenation reduction of 2-hydroxy-2-methoxy-butyric acid.Safety Information:- 3,4-Dihydro-2-methoxy-2H-pyran has low toxicity but should still be used with caution to avoid contact with skin, eyes, and respiratory tract. Personal protective equipment such as protective gloves, face shields and goggles should be worn when in use.- Avoid contact with harmful substances such as strong oxidants and strong acids to avoid dangerous reactions.- Maintain a well-ventilated environment and keep away from fire and high temperatures during handling and storage.- When disposing of waste, it is necessary to comply with the relevant regulations of the local government to protect the environment and personal safety.

Application
3,4-Dihydro-2-methoxy-2H-pyran (CAS 4454-05-1) is a high-purity cyclic enol ether widely used as a key pharmaceutical intermediate and organic building block in chemical R&D. Its primary application is hydrolysis to produce glutaraldehyde, a high-efficiency disinfectant and crosslinking agent used in water treatment, leather tanning, and industrial biocides. As a versatile monomer and synthetic equivalent of acrolein, MDP is essential for constructing complex heterocyclic scaffolds including dihydropyranones, pyridazines, piperidines, and various N-, O-heterocyclic compounds. In drug discovery, its scaffold appears in the syntheses of pharmaceuticals including the anticoagulant edoxaban, the antibiotic linezolid, and potential anti-cancer agents. MDP also serves as a reactive hydroxyl protecting group and a pharmaceutical intermediate for anti-hypertensive and antiviral APIs. As a specialty monomer in polymer chemistry, it improves adhesion and durability in high-performance coatings and resins. Additional applications include agrochemical synthesis, flavor and fragrance formulation, and electronic chemical manufacturing. Xinchem offers reliable custom synthesis, custom chemical synthesis, and contract manufacturing of high-purity 3,4-Dihydro-2-methoxy-2H-pyran with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and global supply.


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