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N-Methyl-N-trimethylsilylacetamide(CAS#7449-74-3)

Chemical Property:

Molecular Formula C6H15NOSi
Molar Mass 145.27
Density 0.904g/mLat 20°C(lit.)
Boling Point 159-161°C(lit.)
Flash Point 48 °C
Vapor Presure 6.41mmHg at 25°C
Appearance lyophilized powder
Specific Gravity 0.906
Color Clear light yellow
BRN 506975
pKa -0.11±0.70(Predicted)
Storage Condition -20°C
Sensitive Moisture Sensitive
Refractive Index n20/D 1.439
MDL MFCD00040758
Use Trimethylsilylation reagents for polar compounds

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N-Methyl-N-trimethylsilylacetamide(CAS#7449-74-3)

Introduction
N-methyl-N-trimethylsilane acetylamide, also known as N-Methyl-N-trimethylsilylacetamide.

Properties: N-methyl-N-trimethylsilane acetylamine is a colorless to yellow liquid with a distinctive ammonia odor. It can be dissolved in common organic solvents at room temperature, such as alcohols, ethers and chlorinated hydrocarbons. This compound is a relatively stable compound, but it may decompose under the action of heat and oxidants.

Usage: N-methyl-N-trimethylsilane acetylamine is widely used as a reagent in organic synthesis. It can be used as a stabilizer, intermediate and precursor to catalysts. In the process of organic synthesis, it is often used in N-methylation reactions, substitution reactions, competitive reduction and other reactions.

Preparation method: N-methyl-N-trimethylsilane acetylamine can be prepared by reacting N-methyl-N-trimethylsilyl ammonia with acetic acid. Among them, N-methyl-N-trimethylsilyl ammonia can be obtained by the reaction of sodium hydrosiliconide and methylamine.

Safety information: N-methyl-N-trimethylsilane acetylamine has low toxicity, but it is still necessary to pay attention to safe operation. It can be irritating to the skin and eyes, and should be rinsed with plenty of water in case of contact. Good ventilation conditions should be maintained during use. The compound should be kept away from ignition sources and oxidizing agents.


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