N,N-bis(trimethylstannyl)methanamine(CAS#1068-67-3)

There are many methods for preparing 4,5-bis (diphenylphosphine) -9,9-dimethyloxanthracene, including direct synthesis and indirect synthesis. The direct synthesis method involves the reaction of phenol and diphenylphosphine chloride to produce the target product under the catalysis of a base. The indirect synthesis method involves first synthesizing intermediates and then further reacting to obtain the target product.

Application
N,N-bis(trimethylstannyl)methanamine (CAS 1068-67-3) is a specialized organotin reagent featuring two trimethylstannyl groups attached to a methanamine core. It serves as a powerful precursor for Stille cross-coupling reactions, enabling the introduction of aminomethyl or substituted methanamine fragments into aryl, heteroaryl, and vinyl halides or pseudohalides. This compound is particularly valuable in pharmaceutical and agrochemical research for constructing complex amine-containing scaffolds, including natural product analogs, kinase inhibitors, and neurotransmitter modulators. The dual stannyl functionality allows sequential or dual coupling, facilitating the synthesis of symmetrical or unsymmetrical diamines and heterocycles. In materials science, it is used to prepare conjugated oligomers and polymers with amine functionality for optoelectronic applications. Due to the labile Sn-C bonds, it also serves as a source of nucleophilic methyleneamine equivalents under transition-metal catalysis. Handling requires standard organotin safety precautions. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of N,N-bis(trimethylstannyl)methanamine with high purity and strict quality control, scalable from R&D to commercial quantities. Contact us today for a competitive quote and reliable global supply.