Fructone (CAS 6413-10-1), chemically ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate or ethyl acetoacetate ethylene glycol ketal, is a cyclic acetal ester fragrance and flavor material with the molecular formula C₈H₁₄O₄ and a molecular weight of 174.19 g/mol. It presents as a clear, colourless liquid with a strong, fruity, apple-green, sweet and woody odour, a boiling point of 125–126 °C at reduced pressure, a flash point of 92–94 °C, a density of 1.083–1.092 g/cm³ at 20 °C, and a refractive index of 1.428–1.435. Its commercial identity rests on a structural fact that separates it from the natural fruit extracts it emulates: Fructone is a synthetic ketal produced by the acid-catalysed reaction of ethyl acetoacetate with ethylene glycol, and it is not found in nature. That synthetic origin is precisely why Fructone has become a reference “apple ketal” in fragrance and flavor creation. It delivers a juicy, diffusive orchard-fruit character—apple, pineapple, strawberry and tropical nuances with a distinctive woody-pine drydown—without the batch variability, colour body and cost volatility of natural apple or pineapple extracts. The global market reflects a compact but structurally important specialty ingredient. As of 2023, the global Fructone market was valued at approximately USD 7 million, with a projected CAGR of 5.78% from 2024 to 2032, driven by consumer preference for fruity profiles, clean-label formulation and the expansion of premium personal care in emerging economies. The qualifying question for buyers is therefore not “what does a kilogram of Fructone cost” but “which grade, purity window and documentation package does my fine-fragrance, personal-care or flavor application actually require”—and, because Fructone is a combustible liquid that is not regulated as dangerous goods, “can my supplier provide the lot-level GC data and Russian-language SDS that qualification demands without adding logistics friction.”
Core Application Fields and Demand Architecture
Fructone demand concentrates in four functional arenas where its juicy orchard-fruit profile and synthetic consistency deliver performance that natural extracts and alternative fruity acetals cannot replicate at equivalent cost and sensory reliability: fine fragrance and perfumery, personal care and household products, flavor and food-adjacent applications, and niche fruity accords and functional fragrance.
In fine fragrance and perfumery, Fructone functions as a heart-note fruity modifier that bridges citrus top notes and woody base notes. It is described as delivering a “strong, fruity, exotic fruit, pineapple, strawberry, apple-like note with a woody aspect reminding of sweet pine”, and it performs “excellently” in fine fragrance according to stability data. Recommended use in perfume concentrates ranges from 0.5% to 30%, reflecting its dosage flexibility: at low levels it adds a juicy lift to floral accords, and at high levels it becomes a defining fruity signature. The specification logic here is purity and odour consistency: a lot that carries an off-note or a colour body will alter the fragrance it is meant to build, and the perfumer discovers the problem after the compound is blended.
In personal care and household products, Fructone is used in soaps, detergents, toiletries, shampoos and lotions to impart a fresh, fruity character and to give the fragrance body and tenacity. Stability data indicate “good” performance in soap and fabric conditioner and “moderate” performance in powder detergent, with poor stability in powder detergent being a known limitation that formulators manage through encapsulation or dosage adjustment. This is the largest volume segment by application breadth, and it values Fructone’s diffusive character and its ability to perform across surfactant systems where natural fruit extracts would be unstable or cost-prohibitive.
In flavor and food-adjacent applications, Fructone is used as a flavoring material in cosmetics, food and beverages, and the manufacture of drugs and detergents. It carries FEMA number 4477 and JECFA number 1969, with JECFA specifications requiring a minimum assay of 98%, an acid value of ≤1, and a refractive index of 1.428–1.435. The specification logic here is the tightest in the portfolio: the material must meet the JECFA monograph and be supported by documentation that satisfies the flavor house’s own regulatory and quality systems. A lot that falls below the 98% assay or carries an acidity excursion cannot be used in a regulated flavor application.
In niche fruity accords and functional fragrance, Fructone is used to create apple, pear and tropical-fruit notes in candles, air care, fabric care and “fruity-floral” creations where a clean, diffusive orchard-fruit effect is required. Its biobased index is below 50%, and it is described as readily biodegradable and vegan suitable, which supports its use in formulations marketed on sustainability criteria. This segment is smaller in volume than personal care but values the same attributes: synthetic consistency, diffusive performance and a clean sensory profile.
Regulatory Profile: TSCA-Listed, IFRA-Unrestricted, Not Regulated for Transport, but a Combustible Liquid with a Flammability Classification
Fructone’s regulatory position is unusually straightforward for a fragrance specialty, which is one of its commercial advantages—but it is not a “documentation-free” material. The operative facts are inventory listings, an IFRA status of “no restrictions,” a combustible-liquid transport regime, and a GHS classification that reflects flammability rather than CMR hazard.
The inventory status is broad and clean. Fructone is listed on the TSCA Inventory in the United States, the IECSC in China, DSL in Canada, AICS in Australia, NZIoC in New Zealand, ENCS in Japan and KECL in Korea, and it carries EINECS 229-114-0 in the EU. The REACH registration number is 01-2119983692-24, and the substance is registered under REACH. That breadth of listing means the material can move through the major regulated markets without a premanufacture notice or new-chemical notification.
The IFRA status is a clear “no restrictions” under the 49th Amendment, with the 51st Amendment also recording “not restricted” for Category 4 and permitted amounts of 100% in finished product where the standard is applied. That is a materially simpler position than many fruity acetals and esters that carry category-specific IFRA limits. The absence of an IFRA standard does not eliminate the need for a current SDS and a lot-specific certificate of analysis, but it removes the reformulation burden that restricted materials impose on fragrance houses.
The GHS classification is dominated by flammability. Fructone carries H227 (combustible liquid) under the GHS criteria applied in some SDS documentation, with precautionary statements focused on keeping away from heat, sparks and open flames, and on wearing protective gloves and eye protection. It is not classified as a CMR substance, and the available SDS documentation does not record carcinogenicity, mutagenicity or reproductive toxicity hazard statements. The flash point of 92–94 °C places it above the threshold for flammable-liquid classification in most jurisdictions, but it remains a combustible liquid that requires appropriate storage and handling precautions.
The transport regime is the practical advantage. Fructone is not regulated for transport under ADR/RID, IMDG or IATA, and the technical data sheet explicitly records “NR” (not regulated) for land, maritime and air transport. That means the material can be shipped by standard freight channels without dangerous-goods surcharges, specialised packaging or segregation requirements—a meaningful cost and lead-time advantage over Class 3 fragrance solvents and intermediates.
The Russian and EAEU position is governed by the same inventory listings and by Russian sanitary-hygienic requirements for workplace air and consumer products. Because Fructone is not regulated for transport and carries no CMR classification, the documentation burden is lighter than for a Class 3 or CMR material, but a Russian-language SDS is still required for customs and downstream qualification, and the buyer’s own product-registration file will require the lot-specific certificate of analysis and, where applicable, the IFRA compliance statement.
Global Supply Structure and Manufacturer Differentiation
Global Fructone supply is a concentrated fragrance-ingredient segment, structured around fragrance houses with the acetalisation capability and the application know-how to produce a consistent apple-ketal profile. The producer landscape identified in market reporting includes Symrise, Givaudan, Takasago, Moellhausen, Berje, Henan Weiyuan Bio-Tech and Shanghai Jiulin Industrial, alongside a cohort of Chinese producers serving domestic and export demand at fragrance and flavor grade. The market is small in absolute value—approximately USD 7 million in 2023—but it is strategically important because Fructone is a building block for fruity accords across fine fragrance, personal care and flavor, and because the material’s synthetic consistency makes it a reliable alternative to natural fruit extracts in cost-sensitive and supply-sensitive formulations.
Differentiation operates on three axes that matter more to a perfumer or a flavor house procurement team than the headline purity figure. The first is odour consistency and purity. Fructone’s value depends on its clean, juicy orchard-fruit profile; a lot that carries an off-note, a colour body or a methyl-isomer excursion above the specification will not deliver the same effect. A supplier that characterises odour against a retained reference and controls the methyl isomer to below 8%—as recorded in one technical specification—gives the buyer a defensible basis for qualification. The second axis is grade breadth and analytical documentation. Fructone is supplied at ≥98% purity for fragrance and flavor use, and the buyer needs a lot-level certificate of analysis that reports assay by GC, acid value, refractive index and density against the agreed specification. A supplier that provides that package, rather than a catalogue nominal, reduces the downstream burden of re-assay and reformulation. The third axis is logistics simplicity and language support. Because Fructone is not regulated for transport, a supplier that can combine standard freight with Russian-language SDS and certificate-of-analysis support offers a lower total qualification and clearance cost than a supplier that treats the material as a dangerous good or leaves the buyer to reconstruct the documentation.
Regional Demand Dynamics
Fructone demand follows the geography of fragrance creation, personal-care manufacturing and flavor production rather than the geography of ethyl acetoacetate or ethylene glycol feedstock.
North America is identified as a leading market, supported by established fragrance manufacturers and a consumer base inclined toward premium personal care and fruity fragrance profiles. Demand is anchored in fine fragrance, personal care and household products, and the region’s regulatory culture places a premium on TSCA listing, current SDS documentation and lot-level analytical data. Europe follows closely, driven by a rich perfumery heritage and growing demand for natural and sustainable fragrance solutions. Fructone’s IFRA-unrestricted status and its ready biodegradability support its position in European formulations, and the region’s fragrance houses value the synthetic consistency that natural apple extracts cannot guarantee.
Asia-Pacific is the emerging growth region, fueled by rapid urbanisation, rising disposable incomes and a growing focus on personal grooming in countries such as China and India. China is a significant producer and consumer, with multiple suppliers listed at fragrance and flavor grade, and the region’s demand is bifurcated between cost-sensitive household and personal-care applications and specification-sensitive fine-fragrance and flavor applications. The documentation bar is rising as export-oriented manufacturers align with European and North American customer expectations.
Russia and the EAEU form an import-dependent contour for a specialty fragrance ingredient. Fructone is supplied as a fragrance and flavor raw material for perfumery, cosmetic and household-product manufacturing, and there is no evidence of large-scale domestic production at fragrance grade. The practical constraints are Russian-language SDS, lot-specific GC data and the not-regulated-for-transport status, which actually simplifies logistics relative to Class 3 materials. The qualification task for Russian buyers is to verify purity, odour consistency and the JECFA-relevant parameters for flavor use, and to secure a Russian-language documentation package that supports customs and downstream product registration.
Future Outlook and Strategic Imperatives
The Fructone market will grow at a mid-single-digit rate—approximately 5.78% CAGR from 2024 to 2032—from a small base, and the quality of that growth is shaped by three structural forces that reward consistency and documentation depth over commodity pricing.
First, the clean-label and natural-origin narrative is a double-edged sword. Fructone is synthetic and not found in nature, so it does not benefit directly from the “natural” claim. But its synthetic consistency, IFRA-unrestricted status and lower cost relative to natural fruit extracts make it a practical choice for formulators who need a reliable fruity profile without the variability of botanicals. Suppliers that can document the synthetic origin, the JECFA compliance for flavor use and the IFRA status will capture the formulations where performance and supply security outweigh the natural-origin label. Second, fruity profiles will continue to expand in personal care and household products. The shift toward premiumisation and “sensorial” formulation in emerging markets is pulling demand for diffusive, long-lasting fruity notes, and Fructone’s 12-hour tenacity on blotter and its performance in soap and fabric conditioner position it well for those applications. Third, logistics simplicity will remain a commercial advantage. Because Fructone is not regulated for transport, suppliers that can ship through standard channels with Russian-language documentation and lot-level GC data offer a lower total cost of qualification than suppliers of Class 3 fruity esters that require dangerous-goods handling.
For Russian and EAEU buyers, the strategic implication is that Fructone procurement should be treated as a grade-and-documentation partnership rather than a price comparison. A lot that falls below the 98% assay or carries an off-odour cannot be corrected by adjusting the dosage; it can compromise a fine-fragrance brief or a flavor application. A shipment that arrives without a Russian-language SDS or without lot-specific GC data can delay customs clearance and downstream registration. The lowest-risk supplier is the one that can match the grade to the application, document assay and odour lot by lot, and support the buyer with Russian-language documentation and standard freight logistics—the position XINCHEM occupies for Fructone in the Russian and EAEU market.
Shanghai XinChem Co., Ltd. (XinChem)
As a world-leading supplier of organic chemicals, Shanghai XinChem Co., Ltd. (XinChem) offers Fructone (CAS 6413-10-1) in fragrance-grade and flavor-grade specifications at ≥98% purity, serving fine-fragrance houses, personal-care and household-product manufacturers, flavor and beverage producers, and specialty fragrance-creation laboratories. Our Fructone is supplied with lot-specific GC assay data, odour characterisation against a retained reference, and the documentation support—including TSCA, IECSC and DSL listing statements, IFRA “no restrictions” confirmation, JECFA-relevant analytical data and Russian-language SDS—that fragrance and flavor qualification requires, delivered through standard freight channels because the material is not regulated for transport.
Technical and Quality Advantages
Purity and Odour Consistency: Fructone is supplied at ≥98% purity (GC), with the methyl isomer controlled and odour characterised against a retained reference lot. Because Fructone’s value depends on a clean, juicy orchard-fruit profile, lot-level sensory and analytical data is the specification that determines whether the material builds a fruity accord or introduces an off-note.
JECFA-Relevant Flavor Documentation: For flavor-grade applications, XinChem provides a certificate of analysis reporting assay, acid value, refractive index and density against the JECFA specification (minimum 98% assay, acid value ≤1, RI 1.428–1.435), supporting the buyer’s own flavor-house qualification and regulatory filing.
IFRA and Inventory Statements: Safety data sheets are available in Russian and English, with documentation covering the IFRA 49th/51st Amendment “no restrictions” status, the TSCA, IECSC, DSL, AICS, NZIoC, ENCS and KECL listings, and the not-regulated-for-transport classification under ADR/RID, IMDG and IATA. This package reduces the qualification and clearance burden for a fragrance specialty that moves through standard logistics channels.
Grade Breadth and Supply Reliability: Fructone is available in fragrance and flavor grades across drum and IBC quantities, with sealed containers for pilot and laboratory qualification. Supply schedules accommodate both qualification orders and recurring contract volumes, with stock planning aligned to the fragrance-ingredient demand cycle and the trade flows that shape Fructone availability.
Packaging and Logistics Flexibility
Fructone is available in 200 kg drums and IBCs for industrial fragrance and flavor operations, and in sealed 1 kg, 5 kg and 25 kg containers for pilot, laboratory and small-batch creation. The product should be stored at 25 °C maximum in a tightly sealed container, protected from light, heat and air, with a shelf life of 36 months under recommended conditions. Because Fructone is not regulated for transport, XinChem can arrange standard freight with Russian-language SDS and certificate-of-analysis support, reducing clearance friction relative to Class 3 fragrance materials.
Application Support and Supply Reliability
XinChem’s technical team assists with grade selection for fine fragrance, personal care, household products, flavor and beverage applications, with dosage guidance consistent with the 0.5–30% use range in perfume concentrates, and with the purity, odour and IFRA documentation that fragrance-house and flavor-house qualification demands. Supply schedules accommodate both small creation quantities and recurring production volumes, with stock planning aligned to the concentrated fragrance-ingredient supply base and the trade flows that shape Fructone availability.
Why Choose XinChem
Expertise: Deep experience in fruity fragrance acetals and ketal esters, with application knowledge spanning fine fragrance, personal care, household products and flavor.
Consistency: Lot-specific control of assay, methyl-isomer content and odour profile—the parameters that determine whether Fructone delivers the intended juicy orchard-fruit effect or becomes a reformulation problem.
Compliance Readiness: Documentation structured around the TSCA/IECSC/DSL listings, the IFRA “no restrictions” status, the JECFA-relevant analytical parameters, and the not-regulated-for-transport classification, with Russian-language SDS support.
Responsiveness: Direct technical and commercial access, with order structures from creation quantities to production-scale supply.
Contact us now to discuss your Fructone requirements and request a specification sheet or qualification sample.
Website: www.xinchem.com
Email: sales1@xinchem.com
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Post time: Nov-12-2026