1,4-Butanediol(CAS#110-63-4)
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R67 - Vapors may cause drowsiness and dizziness |
| Safety Description | S36 - Wear suitable protective clothing. S23 - Do not breathe vapour. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 1 |
| RTECS | EK0525000 |
| TSCA | Yes |
| HS Code | 29053980 |
| Toxicity | LD50 orally in Rabbit: 1525 mg/kg LD50 dermal Rabbit > 2000 mg/kg |
Introduction
Flammable. It tastes bitter. Can be miscible with water, soluble in alcohol, slightly soluble in ether. Solely solidified in the coolant to form colorless needle-like crystals, react with dilute nitric acid to form succinic acid, and produce precipitation when encountering potassium carbonate solution
Application
1,4-Butanediol (BDO, CAS 110-63-4) is a versatile diol used as a solvent, monomer, and chemical intermediate. It is a key raw material for producing tetrahydrofuran (THF), γ-butyrolactone (GBL), and polybutylene terephthalate (PBT) engineering plastics. In polyurethane production, BDO serves as a chain extender for thermoplastic polyurethanes (TPU), elastomers, and adhesives, enhancing flexibility and mechanical strength. It also functions as a humectant and coupling agent in cosmetics and personal care products. In pharmaceuticals, it is an intermediate for the synthesis of anesthetics and antiviral drugs. Additionally, BDO is used in agrochemical formulations, deicing fluids, and as a solvent for resins and dyes. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of high-purity 1,4-butanediol with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.






