(1R,4S)-N-BOC-1-Aminocyclopent-2-ene-4-carboxylic acid(CAS#151907-79-8)

Introduction

(-)-(1S,4R)-N-tert-butoxycarbonyl-4-aminocyclopenta-2-en-1-carboxylic acid, also known as N-Boc-D-Carbofuran-4-aminocarboxylic acid, is an organic compound.Quality:(-)-(1S,4R)-N-tert-butoxycarbonyl-4-aminocyclopenta-2-en-1-carboxylic acid is a solid that is soluble in certain organic solvents, such as ethers and alcohols. It is a chiral compound with a pair of sexual centers, 1S and 4R, respectively.Use:(-)-(1S,4R)-N-tert-butoxycarbonyl-4-aminocyclopenta-2-en-1-carboxylic acid can be used as a reagent and intermediate in organic synthesis.Method:The preparation method of (-)-(1S,4R)-N-tert-butoxycarbonyl-4-aminocyclopenta-2-en-1-carboxylic acid is complex and multi-step. A commonly used method is to react by synthesizing derivatives of the natural product turpentine.Safety Information:During use, care should be taken to prevent inhalation, ingestion, or skin contact, and avoid contact with eyes and skin.When operating, protective gloves, protective glasses and work clothes should be worn to ensure a well-ventilated laboratory environment.In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical assistance.During storage and handling, it needs to be kept dry and airtight to avoid contact with oxygen and moisture.If waste needs to be disposed of, the relevant laws and regulations should be complied with.

Application
(1R,4S)-N-Boc-1-aminocyclopent-2-ene-4-carboxylic acid (Boc-ACPC, CAS 151907-79-8) is a chiral, Boc-protected cyclic γ-amino acid built on a rigid cyclopentene scaffold. As a critical pharmaceutical intermediate, it serves as a key building block for carbocyclic nucleoside analogs, including the anti-HIV agent (-)-carbovir. The combination of a strained olefin, orthogonal Boc protection, and defined stereochemistry enables the construction of conformationally constrained peptides and nucleoside analogs for antiviral (including SARS‑CoV‑2 Mpro targets), antitumor, and antimicrobial drug discovery. It also functions as a peptide isostere to improve metabolic stability and as a reference standard (e.g., Peramivir Impurity 34) for analytical method development and quality control. Xinchem offers high-purity (>98%) Boc-ACPC with flexible custom synthesis and contract manufacturing, scaled from R&D to commercial tons. Contact us for a competitive quote.