2-Methyl-1-phenyl-1,3-butanedione(CAS#6668-24-2)

Introduction

2-METHYL-1-PHENYL-BUTANE-1,3-DIONE is an organic compound. The properties of the compound are as follows:- Appearance: Colorless crystalline solid 2-methyl-1-phenyl-1,3-butanedione has a wide range of applications in the chemical and pharmaceutical industries:- As a reaction intermediate in organic synthesis- For the synthesis of dyes and pigments The compound can be synthesized by the following methods: by phenylethanol by acylation and carbonyl hydrogenation reactions to produce the target product. - The compound is irritating, avoid contact with skin and eyes. - Proper laboratory procedures should be followed during handling and appropriate personal protective equipment such as gloves and safety glasses should be worn. - It should be used in a well-ventilated area and avoid inhaling its vapors. - Avoid contact with strong oxidizing agents to avoid dangerous reactions. In all cases, safety data sheets and operating guidelines should be carefully studied and followed when using chemicals, and handled and stored in accordance with relevant regulations.

Application

2-Methyl-1-phenylbutane-1,3-dione (CAS 6668-24-2) is a substituted β-diketone widely used as a pharmaceutical intermediate, organic synthesis building block, and ligand in coordination chemistry. In medicinal chemistry, it serves as a key intermediate for the synthesis of multifunctional agents targeting Alzheimer's disease, particularly through conjugation with tacrine derivatives to create dual cholinesterase inhibitors and neuroprotective compounds. As a versatile synthetic scaffold, this β-diketone participates in aldol condensations, Michael additions, and heterocycle formations, enabling rapid construction of bioactive libraries for drug discovery. In coordination chemistry, it acts as an O,O'-bidentate ligand to form stable metal complexes with transition and alkaline earth metals (magnesium, calcium), which are of interest for catalysis, material science, and development of metal-organic frameworks (MOFs). This diketone derivative also serves as a dye intermediate, chemical biology probe, and agrochemical synthesis precursor. High purity ensures reproducible results in structure-activity relationship (SAR) studies and scalable GMP manufacturing for pharmaceutical R&D. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of high-purity 2-Methyl-1-phenylbutane-1,3-dione with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.