2,2,2-Triflouoroethanol(CAS#75-89-8)
| Risk Codes | R10 - Flammable R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes R62 - Possible risk of impaired fertility R38 - Irritating to the skin R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S39 - Wear eye / face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S16 - Keep away from sources of ignition. |
| UN IDs | UN 1986 3/PG 3 |
| WGK Germany | 1 |
| RTECS | KM5250000 |
| TSCA | Yes |
| HS Code | 29055910 |
| Hazard Note | Flammable/Toxic |
| Hazard Class | 3 |
| Packing Group | III |
| Toxicity | LD50 orally in Rabbit: 240 mg/kg LD50 dermal Rat 1680 mg/kg |
Introduction
Trifluoroethanol is a colorless liquid with a specific odor.Trifluoroethanol is highly soluble and soluble in many organic solvents, such as ethers and ketones. It is also dissoluble in water.Trifluoroethanol has good solvent properties and surface activity properties, and can be used as an extractive agent, solvent, detergent and cleaning agent. Trifluoroethanol can also be used as a proton exchange membrane material in fuel cells.A common method for preparing trifluoroethanol is by reacting trifluoromethyl sulfonic acid with alcohol. Specifically, trifluoromethyl sulfonic acid reacts with alcohols under acidic conditions to produce the corresponding trifluoroethylene intoxication.It is a flammable substance that avoids contact with open flames, high temperatures, or oxidizing agents. It is also an irritating substance that can cause irritation when it comes into contact with the skin and eyes. When using it, you should pay attention to wearing protective glasses, gloves, protective clothing, etc. If accidentally exposed, rinse immediately with plenty of water and seek medical attention.
Application
2,2,2-Trifluoroethanol (TFE, CAS 75-89-8) is a fluorinated alcohol with unique physicochemical properties, including strong hydrogen-bond donating ability, high polarity, and excellent thermal and chemical stability. It is widely used as a solvent in organic synthesis, electrochemistry, and polymer processing, particularly for reactions requiring polar, non-nucleophilic media. In the pharmaceutical industry, TFE serves as a key intermediate and reaction solvent for the synthesis of peptides, anesthetics, and other active pharmaceutical ingredients (APIs). It is also employed in the production of agrochemicals, fluorinated surfactants, and specialty coatings. Due to its ability to stabilize protein structures, it is used in biochemical research. Additionally, TFE is an effective cleaning agent for electronic components and precision instruments. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of high-purity 2,2,2-trifluoroethanol with flexible scaling from R&D to commercial volumes. Contact us today for a competitive quote and reliable global supply.
