3-Chloro-6-hydrazinopyridazine(CAS#17284-97-8)

Introduction

3-Chloro-6-hydrazinopurine is an organic compound. The following is an introduction to its nature, use, manufacturing methods and safety information:Quality:- Appearance: 3-chloro-6-hydrazidazine is a white crystalline solid.- Solubility: Soluble in hot water, chloroform and methanol.Use:3-Chloro-6-hydrazidazine has a wide range of applications:- As a synthesis reagent: It can be used in organic synthesis reactions, such as chlorination, coupling and nanoparticle preparation.Method:3-Chloro-6-hydrazinazine can be prepared by:- 5,6-Dichloropyridazine is reacted with hydrazine under alkaline conditions to produce 3-chloro-6-hydrazinylpyridazine.Safety Information:The safety of 3-chloro-6-hydrazine, here are some things to look out for:- 3-Chloro-6-hydrazidazine should be considered a hazardous substance and appropriate safe handling measures should be taken, such as wearing protective gloves and glasses.- Avoid inhaling its dust or vapors and avoid direct skin contact.- Maintain good ventilation conditions during use.- When storing, it should be sealed and stored in a dry, cool place to avoid contact with oxidants.

Application
3-Chloro-6-hydrazinopyridazine (CAS 17284-97-8) is a versatile heterocyclic building block featuring a chlorine atom at the 3-position and a hydrazine group at the 6-position. This pyridazine derivative is widely used in medicinal chemistry and pharmaceutical research as a key intermediate for the synthesis of biologically active molecules, including kinase inhibitors, antimicrobial agents, and anti-inflammatory compounds. The hydrazine moiety enables the construction of pyridazinone, triazole, and pyrazole derivatives via cyclocondensation reactions, while the chlorine atom allows nucleophilic aromatic substitution and cross-coupling reactions (Suzuki-Miyaura, Buchwald-Hartwig) for further diversification. This scaffold facilitates rapid structure-activity relationship (SAR) studies in drug discovery, particularly for developing targeted cancer therapies and central nervous system (CNS) agents. It is also utilized in agrochemical research for herbicide and fungicide development. High purity ensures reproducible results in high-throughput screening and scalable GMP synthesis. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of 3-chloro-6-hydrazinopyridazine with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.