3-(Dichloromethyl)benzyl isocyanate(CAS#2241290-41-3)
(1-(Dichloromethyl)-3-(isocyanatomethyl)benzene) or 3-(Dichloromethyl)benzyl isocyanate(CAS#2241290-41-3)
purpose
Mainly used in organic synthesis as an intermediate to participate in the preparation of various compounds containing isocyanate groups.
Safety Information
Health hazards: May cause irritation to the skin, eyes, and respiratory tract, and long-term exposure may pose a risk of cancer.
Operation protection: During operation, protective clothing, gloves, and goggles should be worn to ensure good ventilation and avoid inhaling vapors or skin contact.
Storage: Seal and store in a cool, ventilated place, away from sources of fire and heat.
Precautions
Strictly follow safety operating procedures and avoid direct contact and inhalation.
If a leak occurs, immediate measures should be taken to clean it up and prevent it from entering the environment.
Application
3-(Dichloromethyl)benzyl isocyanate (CAS 2241290-41-3) is a specialized bifunctional isocyanate containing both a dichloromethyl group and a benzyl isocyanate moiety. This unique structure makes it a valuable intermediate for pharmaceutical and agrochemical synthesis. The isocyanate group readily reacts with alcohols, amines, and thiols to form urethanes, ureas, and thiocarbamates, while the dichloromethyl group can participate in further functionalization reactions such as nucleophilic substitution or hydrolysis to aldehyde. It is primarily used in the development of novel drug candidates, particularly protease inhibitors and anticancer agents. In materials science, it serves as a monomer for polyurethane coatings and adhesives with enhanced chemical resistance and thermal stability. The compound also finds application in the synthesis of heterocyclic scaffolds and photoactive materials. High purity is critical for reproducible results in sensitive organic transformations. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of 3-(dichloromethyl)benzyl isocyanate with strict quality control and flexible scaling from R&D to commercial volumes. Contact us today for a competitive quote and reliable global supply.
