Acrolein dimethyl acetal(CAS#6044-68-4)
| Hazard Symbols | F - Flammable |
| Risk Codes | 11 - Highly Flammable |
| Safety Description | S16 - Keep away from sources of ignition. S23 - Do not breathe vapour. S24/25 - Avoid contact with skin and eyes. S29 - Do not empty into drains. S33 - Take precautionary measures against static discharges. |
| UN IDs | UN 3384 6.1/PG 1 |
| WGK Germany | 3 |
| RTECS | UC8500000 |
| Hazard Class | 3.1 |
| Packing Group | II |
Introduction
Acrolein dimethylacetal. The following is an introduction to its nature, use, preparation method and safety information:Quality:Acrolein dimethylacetal is a colorless to yellowish liquid with a peculiar odor. It is soluble in many organic solvents such as alcohols, ethers, and esters, but insoluble in water.Use:Acrolein dimethylacetal has a wide range of applications in the field of organic synthesis. It can be used as an intermediate in the synthesis of compounds of different classes, such as ketones, carboxylic acids, and alcohols. It can also be used as a starting material for the preparation of resins, plastics, dyes, and adhesives.Method:Acrolein dimethylacetal can be prepared by the esterification reaction of acrolein and methanol. In general, a dialkyl acid catalyst is added to the reaction system, and the reaction is heated to esterify acrolein and methanol to form acrolein dimethylacetal.Safety Information:1. When exposed to acrolein dimethylacetal, wear appropriate protective gloves, goggles, and protective clothing.2. Avoid inhaling acrolein dimethylacetal gases or vapors, and operate or wear respiratory protective equipment in a well-ventilated area.3. Avoid prolonged skin contact, if it comes into contact with the skin, rinse immediately with plenty of water.5. When storing, acrolein dimethylacetal should be sealed and stored in a cool, dry place, away from fire and oxidants.
Application
Acrolein dimethyl acetal (3,3-Dimethoxy-1-propene, CAS 6044-68-4) is a versatile organic building block widely used as a stabilized equivalent of highly reactive acrolein. The compound serves as a key pharmaceutical intermediate and advanced synthetic reagent for constructing heterocyclic compounds, amino acids, and various biologically active molecules. As a protecting group reagent, it safeguards aldehyde functionalities during multi-step syntheses, with deprotection achievable under mild acidic conditions. This acetal participates in nucleophilic additions, cross-metathesis reactions, and cationic copolymerization with ethene to produce branched polymers. In agrochemical development, it contributes to the synthesis of insecticides and herbicides. The compound is also utilized in fragrance formulations, though its primary value lies in precision organic synthesis. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of high-purity acrolein dimethyl acetal with flexible scaling from R&D to commercial tons. Contact us for a competitive quote.







