Ethyl 3-(2-iodophenyl)-3-oxopropanoate（CAS# 90034-85-8)

Introduction

Ethyl 3-(2-iodophenyl)-3-oxopropionate is an organic compound. The following is an introduction to its nature, use, manufacturing methods and safety information:

Quality:

Ethyl 3-(2-iodophenyl)-3-oxopropionate is a colorless and transparent liquid. It has good solubility in solvents and is soluble in organic solvents such as ethanol, chloroform and methylene chloride.

Use:

Ethyl 3-(2-iodophenyl)-3-oxopropionate has important application value. It is commonly used in C-C coupling reactions in organic synthesis, such as Suzuki coupling reaction and Stille coupling reaction.

Method:

The preparation of ethyl 3-(2-iodophenyl)-3-oxopropionate can be prepared by the reaction of iodobenzene with ethyl bromoacetate, and then by the treatment of sodium hydroxide and 1-(dimethylamino)methanol. Specific synthesis methods need to be carried out under laboratory conditions, and reaction conditions and treatment processes need to be tightly controlled.

Safety Information:

Ethyl 3-(2-iodophenyl)-3-oxopropionate has a high safety profile, but appropriate safety measures are still required. In case of contact with skin and eyes, rinse immediately with plenty of water. Open flames and high temperatures should be avoided during operation and storage. Appropriate protective equipment such as gloves, glasses, and protective masks should be worn during operation to ensure personal safety.

Application