Ethyl 3-mercaptopropionate(CAS#5466-06-8)
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| HS Code | 29309090 |
Introduction
Ethyl 3-mercaptopropionate is an organic compound. The following is an introduction to the properties, uses, preparation methods and safety information of the compound:Quality:Appearance: Colorless liquidSmell: Slightly sulphurousDensity: 1.030 g/cm³Solubility: insoluble in water, soluble in organic solvents such as ethanol and ether.Use:Chemical reagent: It is often used as a vulcanization reagent in organic synthesis reactions, which can be used to synthesize organic compounds with special functions.Crosslinker: It can be used as a crosslinker for polymers to improve the physical properties and thermal stability of polymers.Method:In general, the preparation method of ethyl 3-mercaptopropionate is as follows:Ethyl acrylic sulfonate is reacted with sodium thiocyanate to form ethyl 3-mercaptopropionate. The reaction conditions and specific steps can be adjusted according to the actual needs. It can also be synthesized by other methods.Safety Information:Ethyl 3-mercaptopropionate is strongly irritating and should be avoided in contact with the skin and eyes, and avoidance of its vapors should be avoided.Appropriate personal protective equipment such as laboratory gloves and goggles should be worn during operation.Avoid contact with strong oxidizing agents and strong acids to avoid dangerous reactions.When storing and handling, appropriate safety measures should be followed and good ventilation should be maintained.
Application
Ethyl 3-mercaptopropionate (CAS 5466-08-8, FEMA 3677) is a colorless to pale yellow liquid organosulfur compound used across multiple industries. As a FEMA 3677 flavor ingredient, it imparts pleasant fruity, grapy, rhubarb, and empyreumatic (roasted/smoky) characters at low concentrations, and is naturally found in cheese, wine, Concord grape, and mountain papaya. As a key pharmaceutical intermediate, this ester serves as a versatile organic building block for preparing HIV protease inhibitors and anti-MRSA cephalosporins, and is also used as Sugammadex reference standard for analytical method development, ANDA filings, and QC applications. In polymer chemistry, it acts as a crosslinking agent to improve polymer physical properties and thermal stability, and as a sulfhydration reagent for synthesizing organic compounds with special functions. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of high-purity ethyl 3-mercaptopropionate with comprehensive characterization data, compliant with regulatory guidelines, and flexible scaling from R&D to commercial tons. Contact us for a competitive quote and reliable global supply.







