Fmoc-Pro-OH (CAS# 71989-31-6)

Chemical Property:

Molecular Formula C20H19NO4

Molar Mass 337.37

Density 1.2486 (rough estimate)

Melting Point 117-118°C(lit.)

Boling Point 473.68°C (rough estimate)

Specific Rotation(α) -32 º (c=1,DMF)

Flash Point 285.6°C

Solubility Soluble in methanol. (almost transparency.)

Vapor Presure 7.19E-13mmHg at 25°C

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Product Detail

Product Tags

Application

Fmoc-L-proline is an amino acid derivative, it can be prepared by one-step reaction of L-proline with 9-fluorenyl methyl chloroformate or 9-fluorenylmethyl-n-succinimidyl carbonate. It has been reported in the literature to be useful in the preparation of a novel antidepressant drug candidate Rapastinel(GLYX-13).

Specification

Appearance White to bright yellow crystals
Color White to Off-White
BRN 3596735
pKa 3.95±0.20(Predicted)
Storage Condition Store below +30°C.
Refractive Index -32.5 ° (C=1, DMF)

Safety

Risk Codes 36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S24/25 - Avoid contact with skin and eyes.
WGK Germany 3
HS Code 2933 99 80