Latanoprost(CAS#130209-82-4)

 Latanoprost(CAS#130209-82-4)

quality
Colorless to yellowish oily. Highly soluble in acetonitrile, soluble in acetone, ethanol, ethyl acetate, isopropanol, methanol or octanol, almost insoluble in water.

Method
3,3a.4.5.6.6a-hexahydro-2-oxo-4-hydroxymethyl-5-(4-phenybenzoyloxy)-2H-cyclopentane[b] was used as the starting material, and it was obtained by several steps of reaction.

use
Developed by Pharmacia & Up-john in Switzerland and the United States, it was launched in the United States in 1996. Glaucoma and ocular hypertension, as well as various conditions of increased intraocular pressure.

Application
Latanoprost (CAS 130209-82-4) is a prostaglandin F2α analog and a first‑line active pharmaceutical ingredient for the reduction of elevated intraocular pressure in patients with open‑angle glaucoma or ocular hypertension. It acts as a selective FP receptor agonist that increases aqueous humor outflow primarily through the uveoscleral pathway, effectively lowering IOP by 20‑30% with once‑daily dosing. Its prodrug nature ensures rapid corneal penetration and in situ activation. Beyond its core ophthalmic use, Latanoprost also promotes eyelash growth, finding application in cosmetic products. The compound is manufactured under GMP standards, meets USP/EP monographs, and is supported by regulatory filings (DMF). Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of high-purity Latanoprost, ensuring reliable global supply and seamless scale‑up from R&D to commercial production.