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A High-Purity Fatty Alcohol for Cosmetics, Lubricants & Pharmaceutical Excipients: Octadecanol (CAS: 112-92-5)

Octadecanol (1-octadecanol, stearyl alcohol, CAS: 112-92-5) is a long-chain saturated fatty alcohol with the molecular formula C18H38O. Its structure consists of an 18-carbon linear alkyl chain terminated by a primary hydroxyl group, imparting both hydrophobic and hydrophilic characteristics. As a versatile industrial intermediate, octadecanol exhibits excellent emulsifying, thickening, and lubricating properties, making it indispensable in personal care formulations (creams, lotions, hair conditioners), pharmaceutical ointments and suppositories, plastic lubricants and release agents, as well as textile softeners and antifoaming agents. Its production typically involves hydrogenation of stearic acid or methyl stearate, or reduction of natural fats and oils. Market demand is closely linked to the global cosmetics industry’s preference for non‑ionic emulsifiers, the expansion of pharmaceutical topical dosage forms, and the need for high-performance industrial lubricants. Based on its chemical characteristics and industrial chain position, this article systematically analyzes international market dynamics of octadecanol, focusing on core application scenarios, competitive landscape, regional differences, regulatory trends, and future outlook, providing strategic references for industry participants.

Core Application Fields and Demand
Market demand for octadecanol is highly concentrated in three major areas: cosmetics and personal care (≈50% of global consumption), pharmaceutical excipients (≈25%), and industrial lubricants & plastic additives (≈25%). Its amphiphilic nature and excellent safety profile drive its widespread adoption.

In the cosmetics and personal care sector, octadecanol is used as an emollient, thickener, emulsion stabilizer, and opacifying agent in creams, lotions, sunscreens, shampoos, conditioners, and deodorants. It imparts a smooth, non‑greasy afterfeel and improves the consistency of formulations. Global leading brands demand high‑purity stearyl alcohol with low odor, low residual alcohol (C16/C18 ratio controlled), and compliance with cosmetic safety standards (EU Cosmetic Regulation EC 1223/2009, US FDA CIR). The global personal care market, growing at 4‑5% annually, sustains robust demand for high‑quality octadecanol.

In the pharmaceutical sector, octadecanol serves as a pharmaceutical excipient in topical ointments, creams, suppositories, and oral tablet coatings. It acts as a stiffening agent, lubricant, and release modifier. Its biocompatibility and low irritation profile make it suitable for dermatological and mucosal applications. The global pharmaceutical excipients market expands at 5‑6% per year, with increasing demand for natural‑derived and high‑purity fatty alcohols.

In industrial applications, octadecanol is used as a lubricant and release agent in plastics processing (PVC, polyolefins), as an antifoam agent in papermaking and water treatment, and as a raw material for the synthesis of surfactants, emulsifiers, and ester lubricants. The global industrial lubricant additive market grows at 3‑4% annually.

Major Market Participants
The global supply system for octadecanol (CAS: 112-92-5) presents a pattern of “large‑scale oleochemical producers dominating volume supply, with specialty manufacturers focusing on high‑purity and custom blend grades.” Production relies on hydrogenation of vegetable oil‑derived stearic acid or direct reduction of natural fatty acids.

In the global high‑volume segment, major oleochemical producers in Southeast Asia (Malaysia, Indonesia) and Europe have significant capacities. However, Shanghai XinChem Co., Ltd. (XinChem) has established a reliable supply chain for high‑purity octadecanol with consistent quality, low residual C16 alcohols, and strict control of heavy metals and water content, serving customers in cosmetics and pharmaceuticals worldwide.

In the high‑purity pharmaceutical and R&D segment, several European and US fine chemical companies offer octadecanol for excipient applications. XinChem provides a cost‑effective, scalable alternative with custom packaging options for both research and commercial quantities.

Regional Market Dynamics
Global demand for octadecanol shows regional differentiation: “Asia‑Pacific dominates production and consumption (over 55%), North America and Europe lead in high‑purity pharmaceutical and cosmetic applications, and Latin America & Middle East/Africa follow as growth markets for personal care.”

Asia‑Pacific is the world‘s largest producer and consumer of octadecanol. China, Malaysia, and Indonesia have integrated palm oil‑based oleochemical complexes, supplying industrial and cosmetic grades to domestic and export markets. India consumes significant volumes for pharmaceutical excipients and personal care products. Japan and South Korea demand ultra‑high‑purity grades for premium cosmetic formulations.

North America and Europe account for approximately 30-35% of global demand, focused on high‑purity (≥99%, C18 >95%) material for pharmaceutical ointments, natural cosmetics, and controlled‑release formulations. Regulatory documentation (COA, residual solvents, heavy metals, European Pharmacopoeia or USP compliance) is strictly required.

Latin America and Africa are growth markets for personal care and pharmaceutical products, with increasing local manufacturing. Price sensitivity is higher, and Asian suppliers dominate trade flows.

Regulatory and Environmental Considerations
As a cosmetic ingredient and pharmaceutical excipient, octadecanol (CAS: 112-92-5) is subject to safety and purity regulations in major economies.

In the EU, octadecanol is permitted as a cosmetic ingredient and is listed in the CosIng database. For pharmaceutical use, it must comply with the European Pharmacopoeia (Ph. Eur.) monograph. Under REACH, it is registered as a chemical substance. The compound is not classified as hazardous; it is considered a non‑irritant and non‑sensitizing under normal use.

In the US, the FDA lists stearyl alcohol as a Generally Recognized as Safe (GRAS) indirect food additive and as an approved excipient in OTC and prescription topical drug products (21 CFR). The Cosmetic Ingredient Review (CIR) has deemed it safe for use in cosmetics.

In China, octadecanol is included in the “Inventory of Existing Chemical Substances” and the “Safety and Technical Standards for Cosmetics” (2015 Edition) as an allowed raw material. Manufacturers require safety production licenses. In Japan, it is regulated under CSCL and is listed in the Japanese Pharmaceutical Excipients Directory.

Environmentally, octadecanol is biodegradable and has low eco‑toxicity. Production via hydrogenation generates spent catalysts requiring recycling. Green chemistry efforts focus on using renewable feedstocks (palm oil, coconut oil) and energy‑efficient hydrogenation processes.

Future Outlook
The market outlook for octadecanol is tied to three drivers: sustained growth of the global personal care industry, increasing demand for natural and plant‑derived pharmaceutical excipients, and the expansion of industrial lubricant additives. The global market is expected to grow at a CAGR of 3‑5% over the next five years.

On the demand side, first, the rising middle class in Asia‑Pacific and Latin America drives consumption of creams, lotions, and hair care products. Second, the shift toward “green” and natural formulations in cosmetics and pharmaceuticals increases preference for vegetable‑derived octadecanol. Third, the growth of electric vehicles and high‑performance engineering plastics requires specialty lubricant additives and release agents.

Challenges include: raw material price volatility (palm oil, palm kernel oil, coconut oil), competition from synthetic alternatives (C16/C18 blends from petrochemical sources), and environmental concerns over palm oil cultivation. Enterprises should focus on securing certified sustainable palm oil feedstocks, developing high‑purity pharmaceutical‑grade products, and investing in continuous hydrogenation technology.

Shanghai XinChem Co., Ltd. (XinChem)
As a world‑leading supplier of organic chemicals and specialty ingredients, Shanghai XinChem Co., Ltd. (XinChem) has always focused on the innovative needs of the personal care, pharmaceutical, and industrial lubricant industries. Relying on core technological advantages in fatty alcohol purification and hydrogenation, we provide high‑purity Octadecanol (stearyl alcohol, CAS: 112-92-5) to global customers. Our product is manufactured under strict quality management, achieving consistent purity (≥99%) with low C16 content, low water, and low acid value, fully complying with cosmetic and pharmaceutical standards. It is an ideal emollient, thickener, and pharmaceutical excipient.

1. Technical Advantages

  • High Purity: Our octadecanol achieves purity ≥99% (GC) with typical C18 content ≥95%, C16 content <3%, water <0.2%, and acid value <0.1 mg KOH/g.
  • Low Impurity Profile: Strict control of residual fatty acids, heavy metals (≤10 ppm), and peroxide value.
  • Batch Consistency: Batch‑to‑batch variation controlled within 0.2% for key indices (hydroxyl value, melting point 56-60°C).

2. Product Advantages

  • Excellent Emulsifying & Thickening Properties: Forms stable oil‑in‑water emulsions and increases viscosity of formulations.
  • Good Biodegradability & Safety: Suitable for skin‑contact applications; complies with global cosmetic and pharmaceutical regulations.
  • Flexible Packaging: 25KG kraft paper bags (industrial), 20KG plastic drums (pharmaceutical), 5KG/1KG aluminum foil bags (R&D), custom packaging upon request.
  • Reliable Supply Chain: Annual capacity 500-1,000 tons, with dedicated cool, dry storage (ambient temperature, avoid humidity).

3. Application Fields

  • Cosmetics & Personal Care: Creams, lotions, sunscreens, hair conditioners, deodorants, lip balms.
  • Pharmaceutical Excipients: Ointments, creams, suppositories, oral tablet coatings, topical gels.
  • Industrial Additives: Plastic lubricants and release agents (PVC, polyolefins), antifoam agents, textile softeners.

4. Service Support
Our technical team provides impurity profiling, custom blending (C16/C18 ratios), and regulatory support (COA, residual solvents analysis, REACH/TSCA compliance, USP/Ph. Eur. documentation). We offer just‑in‑time delivery and competitive pricing for both research quantities and bulk orders.

5. Why Choose XinChem

  • Professionalism: 20+ years in chemical and specialty ingredients.
  • Flexibility: Tailored to customer purity, C18 content, and packaging requirements.
  • Cost‑effectiveness: High quality at competitive prices.

Contact us now to start cooperation!
Website: www.xinchem.com
Email: sales1@xinchem.com
WhatsApp: +86 18049800532


Post time: Apr-27-2026