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Pyrimidine(CAS#289-95-2)

Chemical Property:

Molecular Formula C4H4N2
Molar Mass 80.09
Density 1.055g/cm3
Melting Point 20-22℃
Boling Point 122.4°C at 760 mmHg
Flash Point 31.1°C
Water Solubility soluble
Vapor Presure 16.8mmHg at 25°C
Appearance Form Liquid, color Clear colorless to orange
pKa 1.23(at 20℃)
Storage Condition Flammables area
Stability Stable, but air-sensitive and hygroscopic. Incompatible with acids, acid chlorides, acid anhydrides, strong oxidizing agents, carbon dioxide. Flammable.
Sensitive Easily absorbing moisture
Refractive Index 1.503
MDL MFCD00006059
Physical and Chemical Properties Melting Point: 19-22°CBoiling Point: 123-124°C

density: 1.016g/mL at 25°C

Use Used as raw materials for pharmaceutical intermediates, photosensitizers, etc

Product Detail

Product Tags

Risk Codes R10 - Flammable
Safety Description S16 - Keep away from sources of ignition.
S23 - Do not breathe vapour.
S24/25 - Avoid contact with skin and eyes.
UN IDs UN 1993
WGK Germany 3
RTECS UV6263000
TSCA Yes
HS Code 29335990
Hazard Class 3
Packing Group III

 

Introduction

Soluble in water, ethanol and ether

Application
Pyrimidine (CAS 289-95-2) is a fundamental nitrogen-containing heterocycle and a key building block in organic synthesis, serving as a critical pharmaceutical intermediate and agrochemical raw material. As an essential starting material, it is widely used in the synthesis and discovery of antiviral medications, including treatments for HIV and HSV. It is also employed in the synthesis of potent inhibitors of 15-lipoxygenase, an enzyme involved in leukotriene release. In oncology research, pyrimidine derivatives are studied for applications in pancreatic cancer, triple-negative breast cancer, and colon carcinoma. In crop protection, pyrimidine derivatives function as herbicides by inhibiting acetolactate synthesis and suppressing chlorophyll production in weeds, as well as serving as insecticides and fungicides. The compound acts as a nucleobase analog and is integral to DNA and RNA research. It is also utilized as a solvent and reagent in analytical chemistry, enhancing the sensitivity and accuracy of chemical analyses. As an endogenous metabolite, pyrimidine interacts with various enzymes and proteins, making it a valuable tool for biochemical research. Xinchem offers custom synthesis and contract manufacturing of high-purity pyrimidine with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.


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