Product Name and CAS Number

Tetrahydrofuran THF | CAS 109 99 9

One Line Sourcing Position

High purity Tetrahydrofuran for polymerization solvents, Grignard reactions, and specialty chemical applications.

Quick RFQ Form

Fill below to get instant quote:
Name Email Company Required quantity Delivery destination Submit

Specification

Purity by GC: 99.9 percent minimum, typical batch 99.95 percent
Appearance: Colorless clear liquid
Odor: Ethereal, characteristic
Density at 20 deg C: 0.886 to 0.890 g per mL
Refractive index nD20: 1.407 to 1.409
Boiling point: 65 to 67 deg C
Water content Karl Fischer: 0.03 percent maximum (0.01 percent for anhydrous grade)
Peroxide content: 10 ppm maximum (as hydrogen peroxide equivalent)
Stabilizer: 150 to 250 ppm BHT for inhibited grade; uninhibited grade available
Color APHA: 10 maximum
Residue on evaporation: 0.002 percent maximum
Stock Status: In Stock in US warehouse and China hub

Available Quantity and Lead Time

Regular supply: 1 L to 50 metric tons per shipment
Lead time: 2 to 3 days for standard packaging; bulk orders require 5 to 7 days

Document Support

COA SDS HPLC chromatogram NMR spectrum Mass spectrum MS available upon request

Application

Tetrahydrofuran is a versatile ethereal solvent widely used in industrial and research settings. In polymer chemistry, it serves as the solvent of choice for the polymerization of isoprene, butadiene, and styrene to produce synthetic rubber (e.g., polybutadiene, SBR) via anionic polymerization. THF is also the standard solvent for polytetramethylene ether glycol (PTMEG) production, which is a precursor for spandex fibers and polyurethane elastomers. In laboratory organic synthesis, THF is indispensable for reactions requiring polar aprotic solvents, including Grignard reagent formation, lithium aluminum hydride reductions, hydroborations, and organolithium reactions. It is also used in the preparation of Grubbs catalysts for olefin metathesis and in palladium catalyzed cross coupling reactions (Suzuki, Stille, Negishi). In pharmaceutical manufacturing, THF acts as a reaction medium for the synthesis of active pharmaceutical ingredients such as statins, antivirals, and anticancer agents. In battery research, THF is a component of electrolytes for lithium sulfur and sodium ion batteries. Additionally, it finds use in the production of PVC cements, adhesives, magnetic tape coatings, and as a stripping agent for photoresists in electronics. THF is also a starting material for the synthesis of tetrahydrofurfuryl alcohol and polytetrahydrofuran.

Custom Synthesis Support

We offer custom synthesis for THF derivatives including 2 methyltetrahydrofuran, polytetrahydrofuran (different molecular weights), and anhydrous grades with custom peroxide inhibitor packages. Share your technical datasheet for feasibility review.

Packaging and Shipping

Available in 1 L, 4 L, 20 L, 200 L steel drums, or IBC totes. Also available in isotainers for bulk orders. Custom packaging such as stainless steel cans under nitrogen is supported. Fastest dispatch within 7 days after order confirmation. THF is a highly flammable liquid Class 3, UN 2056, PG II. Store in a cool, well ventilated area away from ignition sources. Peroxide formation is possible; test for peroxides before distillation or prolonged storage. Stabilized (BHT) grades are recommended for general use.

Why XinChem

XinChem provides tetrahydrofuran with stringent control of water content, peroxides, and purity for US customers. Our ISO 9001 certified facility monitors every batch by GC, Karl Fischer, and colorimetric peroxide assay, ensuring consistent performance for sensitive organometallic reactions. We maintain a buffer stock of 30 metric tons in US warehouses for emergency deliveries within 48 hours. Each order includes a full documentation package: COA, SDS, GC chromatograms, and peroxide analysis report accessible through our online portal. Our technical support team assists with handling under inert atmosphere, peroxide inhibition, and regulatory compliance including TSCA, EINECS, and FDA for pharmaceutical manufacturing. For contract customers, we offer quarterly price locks and consignment inventory to reduce supply chain risk. Trusted by over 400 polymer, pharmaceutical, and battery research companies in North America. We also provide free sample evaluation for qualified R&D projects and a price match guarantee against any valid competitor quote for equivalent quality. Anhydrous and ultra low peroxide grades are available upon request for the most demanding applications.

FAQ

Q1 How should tetrahydrofuran be stored to prevent peroxide formation?
A Store in a cool, dark place under inert atmosphere (nitrogen) if possible. Use inhibited grade (BHT stabilized) for long term storage. Test for peroxides every 3 to 6 months. Do not evaporate to dryness. Shelf life of stabilized THF is 24 months.

Q2 What purity and dry grades do you supply?
A Standard purity is 99.9 percent. Anhydrous grade with water below 50 ppm and ultra anhydrous (below 20 ppm) are available. Uninhibited (unstabilized) grade also offered for reactions requiring no additives.

Q3 Is tetrahydrofuran miscible with water?
A Yes, THF is fully miscible with water and most organic solvents including alcohols, ethers, and hydrocarbons.

Q4 Do you provide sample quantities for reaction optimization?
A Yes, free samples of 500 mL are available for qualified US companies. Shipping fee applies for small quantities.

Q5 What are the common impurities in THF and how do you control them?
A Key impurities include water, peroxides, 2 methylfuran, and BHT (if stabilized). Our specification limits water to 300 ppm (standard) and peroxides to 10 ppm. Full impurity profiling is provided.

Q6 Can you supply THF in non returnable containers for overseas shipment?
A Yes, we offer UN approved non returnable steel drums and IBC totes suitable for ocean freight. Please consult our logistics team.

Q7 What safety precautions are necessary when handling THF?
A Use in a fume hood. Avoid ignition sources and static discharge. Wear chemical resistant gloves and goggles. THF is a central nervous system depressant; avoid prolonged vapor inhalation.