Tris(dibenzylideneacetone)dipalladium(CAS#51364-51-3)
Introduction
Tripalladium (0), abbreviated as Pd (dba) 3, is an organic palladium compound. The following is an introduction to its properties, uses, manufacturing methods, and safety information:
nature:
1. Appearance: Pd (dba) 3 is a dark yellow to reddish brown crystalline solid.
2. Solubility: Pd (dba) 3 is soluble in commonly used organic solvents such as chloroform, dimethyl sulfoxide, and dichloromethane.
3. Stability: Stable in air and relatively stable under dry conditions.
Purpose:
1. Catalyst: Pd (dba) 3 is widely used as an effective ligand and catalyst in organic synthesis. It can promote various important reactions, such as coupling reactions (such as Suzuki reaction, Heck reaction, and Sonogashira reaction) as well as other oxidation, reduction, and addition reactions.
2. Proton transfer reaction: Pd (dba) 3 can be used as an acid catalyst in proton transfer reactions.
Manufacturing method:
The preparation method of Pd (dba) 3 is relatively simple, and a common preparation method is obtained by reacting PdCl2 with Allyloxypalladium (II) chloride.
Application
Tris(dibenzylideneacetone)dipalladium (Pd₂(dba)₃, CAS 51364-51-3) is a widely used air-stable palladium(0) complex serving as a versatile precursor for cross-coupling reactions. It is the catalyst of choice for Suzuki-Miyaura, Heck, Stille, Sonogashira, and Buchwald-Hartwig amination, enabling efficient C–C, C–N, and C–O bond formation. Its labile dba ligands are easily displaced by phosphine or NHC ligands, allowing in situ generation of active catalytic species. This complex is essential in pharmaceutical synthesis for constructing complex drug molecules, agrochemical intermediates, and fine chemicals. It also finds applications in materials science for synthesizing conjugated polymers and OLED components. Pd₂(dba)₃ is preferred over Pd(PPh₃)₄ for reactions requiring ligand tuning, as it provides a metal(0) source without phosphine contamination. High purity ensures reproducible catalytic activity. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of Pd₂(dba)₃ with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.







