1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid ethyl ester(CAS#112811-71-9)

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid ethyl ester(CAS#112811-71-9)

Synthesis method
It is usually synthesized with cyclopropylamine, difluorobenzoyl chloride, etc. as starting materials, and then synthesized through multi-step reactions. For example, cyclopropylamine is first substituted with the corresponding halogenated compounds, and then the target product is obtained through a series of reactions such as cyclization, oxidation, and esterification. The exact synthetic route will vary depending on the research and manufacturing needs, and the reaction conditions and reagent selection will also have an impact on yield and purity.
use
It is an important intermediate in the synthesis of quinolone antibacterial drugs such as gatifloxacin and moxifloxacin hydrochloride. Through further structural modification and reaction of this intermediate, different functional groups can be introduced, resulting in quinolones with different antimicrobial activity and pharmacokinetic properties. These drugs are widely used in clinical practice to treat various bacterial infectious diseases, such as respiratory tract infections, urinary tract infections, skin and soft tissue infections, etc.