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8-Quinolinol N-oxide(CAS#1127-45-3)

Chemical Property:

Molecular Formula C9H7NO2
Molar Mass 161.16
Density 1.2480 (rough estimate)
Melting Point 135-138 °C (lit.)
Boling Point 267 °C(lit.)
Flash Point 139 °C
Appearance Form Solid, Color Yellow
pKa 6.03±0.30(Predicted)
Storage Condition Inert atmosphere,2-8°C
Refractive Index 1.5050 (estimate)
MDL MFCD00006739

Product Detail

Product Tags

Risk Codes R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description S60 - This material and its container must be disposed of as hazardous waste.
S61 - Avoid release to the environment. Refer to special instructions / safety data sheets.
S24/25 - Avoid contact with skin and eyes.
S22 - Do not breathe dust.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S27 - Take off immediately all contaminated clothing.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
UN IDs UN 3077 9/PG 3
WGK Germany 3
RTECS VC8238500
FLUKA BRAND F CODES 3-10
HS Code 29334900

 

Introduction

8-Hydroxyquinoline-N-oxide is a toxic substance that can inhibit the luminescence of the indicator bacterial luminescent bacteria. It forms two types of complexes with gold (III) and palladium (II): Type I is an ion-related compound containing hydrogen bonds, and Type II is a six-membered metal chelate containing metal-oxygen bonds.

Application

8-Quinolinol N-oxide (8-Hydroxyquinoline N-oxide, CAS 1127-45-3) is a multifunctional heterocyclic N-oxide serving as a pivotal intermediate in the production of quinolone antibiotics and other active pharmaceutical ingredients (APIs). This building block possesses potent antimicrobial activity against a broad spectrum of bacteria and fungi, making it valuable for pharmaceutical development and crop protection formulations. It also acts as an effective chelating agent, forming stable complexes with metal ions for use in analytical chemistry and industrial corrosion inhibition on metal surfaces. In research, its fluorescent properties enable its use as a molecular probe to study cellular processes. For contract manufacturing and custom chemical synthesis of high-purity 8-Quinolinol N-oxide with global regulatory compliance and flexible scaling from R&D to commercial volumes, Xinchem is a qualified manufacturer and supplier. High-purity product is analytically suitable for QC applications, ANDA filing, method validation, and as a reference standard for Oxyquinoline Sulfate against USP or EP standards. Contact us today for a competitive quote and reliable global supply.


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