1-(pyrimidin-2-yl)ethanone(CAS#53342-27-1)

Introduction

1-(pyrimidin-2-yl)ethanone, chemical formula C7H7NO, is an organic compound. The following is a brief description of its nature, use, preparation and safety information:

Nature:

-Appearance: 1-(pyrimidin-2-yl)ethanone is a white to light yellow crystalline powder.

-Solubility: It dissolves in some organic solvents (such as ethanol, dimethylformamide).

Use:

-Chemical synthesis: 1-(pyrimidin-2-yl)ethanone can be used as chemical synthesis intermediates and play an important role in organic chemical reactions.

-Drug: It is also used in drug research and preparation, for example, as a synthetic intermediate for antiviral, anti-tuberculosis, and anti-cancer drugs.

Preparation Method:

- 1-(pyrimidin-2-yl)ethanone is prepared in a variety of ways, commonly used methods include:

a. is obtained by reacting 2-chloroacetyl chloride with pyrimidine.

B. it is obtained by the reflux reaction of 2-hydroxyacetic acid and pyrimidine in anhydrous ethanol.

Safety Information:

- 1-(pyrimidin-2-yl)ethanone need to be handled and stored in accordance with the safe operation specifications of general organic compounds.

-It may be irritating to the eyes and skin, and direct contact should be avoided.

-Appropriate laboratory safety measures, such as wearing protective glasses, laboratory clothing and gloves, are required for use and handling. At the same time, make sure to operate in a well-ventilated environment and avoid inhaling dust or gas.

-In case of discomfort or maladjustment after contact or inhalation, medical help should be sought promptly.