1,3 Propamediol(CAS#504-63-2)
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 38 - Irritating to the skin |
| Safety Description | S23 - Do not breathe vapour. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 1 |
| RTECS | TY2010000 |
| TSCA | Yes |
| HS Code | 29053980 |
| Toxicity | LD50 orally in Rabbit: 15670 mg/kg LD50 dermal Rabbit > 20000 mg/kg |
Introduction
Sweet. Can be miscible with water and ethanol.
Application
1,3-Propanediol (CAS 504-63-2, PDO) is a versatile, colorless, odorless diol with excellent solvency and low toxicity. It is widely used as a humectant, moisturizer, and skin conditioning agent in cosmetics and personal care products, including creams, lotions, serums, cleansers, and deodorants. Unlike propylene glycol, it offers improved skin feel and reduced irritation. In the polymer industry, it is the key monomer for producing polytrimethylene terephthalate (PTT), a high-performance polyester used in carpets, textiles, engineering plastics, and films. It also serves as an environmentally friendly solvent for coatings, inks, cleaning agents, and antifreeze formulations. In pharmaceuticals, it functions as a solvent, carrier, and intermediate for drug synthesis. Additionally, bio-based 1,3-propanediol derived from renewable resources is increasingly preferred for sustainable manufacturing. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of high-purity 1,3-propanediol with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.







