5- Methyletetrazole(CAS#4076-36-2)
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S24/25 - Avoid contact with skin and eyes. S22 - Do not breathe dust. |
| UN IDs | 1325 |
| WGK Germany | 3 |
| Hazard Note | Flammable/Irritant/Keep Cold |
| Hazard Class | IRRITANT |
| Packing Group | II |
Introduction
Methyltetrazole is an organic compound. The following is an introduction to the properties, uses, preparation methods and safety information of methyltetrazole:Quality:- Appearance: Methyltetrazole is a colorless crystal or white crystalline powder.- Solubility: It is easily soluble in water and most organic solvents such as alcohols, ethers, etc.- Stability: Methyltetrazole is stable at room temperature but burns easily when exposed to high temperatures or open flames.- Chemical properties: It is a strong base that reacts with acidic substances to form corresponding salts.Use:- Textile dyes: Methyltetrazole can be used as dye intermediates to synthesize some dyes with special functions.- Electronic materials: It can also be used to prepare organic semiconductors in electronic materials.Preparation method:- Methyltetrazole can be obtained by reacting dimethylselenium amine with phosphorus dioxide.- Another commonly used preparation method is synthesized by the reaction of formaldehyde, ammonia, and thiourea.Safety Information:- Methyltetrazole is a compound that can be harmful to health and the environment. The following safety measures should be taken when using and storing:- Avoid inhalation, ingestion, and contact with skin and eyes.- Use ventilation equipment well during operation to avoid the accumulation of gases or particulate matter.- Avoid contact with oxidants, acids and other substances when storing.- Waste disposal should comply with local environmental regulations.
Application
5-Methyltetrazole (CAS 4076-36-2) is a nitrogen-rich heterocyclic compound with a tetrazole ring, widely used as a key intermediate in pharmaceutical, agrochemical, and materials science applications. It serves as a bioisostere for carboxylic acids, enhancing metabolic stability and membrane permeability of drug candidates. In the pharmaceutical industry, it is a critical building block for the synthesis of angiotensin II receptor antagonists (e.g., losartan, valsartan), antibiotics, and antiviral agents. It also finds use in the production of high-energy materials, propellants, and gas generants due to its thermal stability and nitrogen content. Additionally, 5-methyltetrazole acts as a ligand in coordination chemistry and as a precursor for specialty polymers. Its high purity is essential for sensitive synthetic routes. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of 5-methyltetrazole with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.







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