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5- Methyletetrazole(CAS#4076-36-2)

Chemical Property:

Molecular Formula C2H4N4
Molar Mass 84.08
Density 1.319±0.06 g/cm3(Predicted)
Melting Point 142-146°C(lit.)
Boling Point 233.3±23.0 °C(Predicted)
Flash Point 116.7°C
Water Solubility Soluble in water.
Solubility Chloroform, DMSO, Methanol
Vapor Presure 0.0561mmHg at 25°C
Appearance Solid
Color White to Off-White
pKa pK1:3.32 (25°C)
Storage Condition Keep Cold
Refractive Index 1.533

Product Detail

Product Tags

Risk Codes 36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S24/25 - Avoid contact with skin and eyes.
S22 - Do not breathe dust.
UN IDs 1325
WGK Germany 3
Hazard Note Flammable/Irritant/Keep Cold
Hazard Class IRRITANT
Packing Group II

 

Introduction

Methyltetrazole is an organic compound. The following is an introduction to the properties, uses, preparation methods and safety information of methyltetrazole:Quality:- Appearance: Methyltetrazole is a colorless crystal or white crystalline powder.- Solubility: It is easily soluble in water and most organic solvents such as alcohols, ethers, etc.- Stability: Methyltetrazole is stable at room temperature but burns easily when exposed to high temperatures or open flames.- Chemical properties: It is a strong base that reacts with acidic substances to form corresponding salts.Use:- Textile dyes: Methyltetrazole can be used as dye intermediates to synthesize some dyes with special functions.- Electronic materials: It can also be used to prepare organic semiconductors in electronic materials.Preparation method:- Methyltetrazole can be obtained by reacting dimethylselenium amine with phosphorus dioxide.- Another commonly used preparation method is synthesized by the reaction of formaldehyde, ammonia, and thiourea.Safety Information:- Methyltetrazole is a compound that can be harmful to health and the environment. The following safety measures should be taken when using and storing:- Avoid inhalation, ingestion, and contact with skin and eyes.- Use ventilation equipment well during operation to avoid the accumulation of gases or particulate matter.- Avoid contact with oxidants, acids and other substances when storing.- Waste disposal should comply with local environmental regulations.

Application
5-Methyltetrazole (CAS 4076-36-2) is a nitrogen-rich heterocyclic compound with a tetrazole ring, widely used as a key intermediate in pharmaceutical, agrochemical, and materials science applications. It serves as a bioisostere for carboxylic acids, enhancing metabolic stability and membrane permeability of drug candidates. In the pharmaceutical industry, it is a critical building block for the synthesis of angiotensin II receptor antagonists (e.g., losartan, valsartan), antibiotics, and antiviral agents. It also finds use in the production of high-energy materials, propellants, and gas generants due to its thermal stability and nitrogen content. Additionally, 5-methyltetrazole acts as a ligand in coordination chemistry and as a precursor for specialty polymers. Its high purity is essential for sensitive synthetic routes. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of 5-methyltetrazole with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.


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