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2 5-DICHLORO-4-METHYLPYRIDINE(CAS# 886365-00-0)

Chemical Property:

Molecular Formula C6H5Cl2N
Molar Mass 162.02
Density 1.319±0.06 g/cm3(Predicted)
Boling Point 219.3±35.0 °C(Predicted)
pKa -1.45±0.10(Predicted)
Storage Condition Inert atmosphere,Room Temperature

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Introduction

2,5-dichloro-4-methylpyriridine is an organic compound with the chemical formula C6H5Cl2N. The following is a description of its nature, use, formulation and safety information:

 

1. nature:

-Appearance: colorless liquid or crystalline solid;

-Solubility: Soluble in organic solvents such as ether, alcohol and hydrocarbons;

-Melting point:-26°C;

-Boiling point: 134-136°C;

-Density: 1.36g/cm³.

 

2. use:

-2,5-dichloro-4-methylpyriridine is an important intermediate in organic synthesis and has a wide range of applications in the field of medicine and chemistry;

-It can be used to prepare pesticides, fungicides and other organic compounds;

-can also be used as a catalyst, surfactant and dye intermediates.

 

3. preparation method:

-The preparation method of 2,5-dichloro-4-methylpyriridine is generally obtained by chlorination reaction on pyridine.

-For example, pyridine can be reacted with phosphorus oxychloride (POCl3) or phosphorus tetrachloride (PCl4) under an inert atmosphere, followed by dechlorination treatment to obtain the target product.

 

4. Safety Information:

-2,5-dichloro-4-methylpyriridine is irritating and corrosive to the eyes, skin and respiratory tract. Flush with plenty of water immediately after contact and seek medical help;

-use should wear protective gloves, protective glasses and protective mask;

-Avoid contact with strong oxidants to avoid dangerous reactions;

-Store away from fire, heat and combustible materials.

Application
2,5-Dichloro-4-methylpyridine (CAS 886365-00-0) is a versatile halogenated pyridine building block. Its primary application is as a key intermediate in the synthesis of various agrochemicals, particularly herbicides and insecticides, where it serves to enhance crop protection and yield. In pharmaceutical research, it plays a crucial role in the synthesis of medicinal compounds, contributing to the development of new drugs targeting specific diseases. It is also used in material science for formulating specialty polymers and coatings to improve durability and chemical resistance. Additionally, this compound serves as a reagent in analytical chemistry for detection and quantification, and is utilized in academic and industrial research for studying reaction mechanisms and developing new synthetic pathways.

 


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