2′-Aminoacetophenone hydrochloride(CAS#25384-14-9)
Introduction
2'-Aminoacetophenone hydrochloride is a white crystalline solid, CAS number 25384-14-9. The preparation method is generally obtained by reacting 2'-aminoacetophenone with hydrochloric acid. The specific preparation process may involve solvents, temperature, and other conditions. Safety Information: 2'-Aminoacetophenone hydrochloride should be handled in accordance with Safe Chemical Practice and avoid inhalation, ingestion, or contact with skin and eyes. Wear appropriate protective equipment such as gloves, goggles, etc. during operation. Waste should be properly disposed of after disposal. During use and storage, safety guidelines should be followed and care should be taken to prevent the risk of fire and explosion.
Application
2'-Aminoacetophenone hydrochloride is a high-purity aromatic ketone that serves as a versatile pharmaceutical intermediate and building block for medicinal chemistry and organic synthesis. The compound's unique ortho-amine and ketone functionalities enable rapid access to heterocyclic scaffolds including indazoles, quinolines, and benzodiazepines. It is a key precursor for the antihypertensive agent etilefrine hydrochloride and is utilized in the synthesis of sirtuin inhibitors with antiproliferative activity against cancer cells. As a stable hydrochloride salt, it is also employed in the preparation of pseudopeptidic inhibitors, dual δ/μ opioid receptor agonists, and antimicrobial agents. Beyond pharmaceutical R&D, 2'-aminoacetophenone HCl is applied in agrochemical development, dye manufacturing, and as an analytical reagent for protein and amino acid quantitation in wine quality control. Xinchem offers flexible custom synthesis and reliable contract manufacturing of this essential building block to support your drug discovery, custom chemical synthesis, and process development programs. Contact us for a competitive quote and dependable global supply.
