2-Chlorobenzylamine（CAS# 89-97-4)
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R34 - Causes burns R37 - Irritating to the respiratory system |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36 - Wear suitable protective clothing. |
| UN IDs | UN 2735 8/PG 2 |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 9-23 |
| TSCA | T |
| HS Code | 29214980 |
| Hazard Note | Irritant |
| Hazard Class | 8 |
| Packing Group | III |
Introduction
Quality:
2,4-Dichlorobenzoyl chloride is a colorless to pale yellow liquid with a pungent odor. It is unstable at room temperature and is easily hydrolyzed and decomposed, so it should be stored under inert gas. It reacts with hydrocarbons, aromatic amines, and alcohols to form corresponding amides and esters.
Use:
2,4-Dichlorobenzoyl chloride is an important intermediate in organic synthesis and has a wide range of applications in organic synthesis reactions. It can be used in the preparation of various benzoyl chloride derivatives and other organic compounds.
Method:
2,4-Dichlorobenzoyl chloride can be obtained by chlorination of p-nitrobenzoic acid or p-aminobenzoic acid. The specific method is to react p-nitrobenzoic acid or p-aminobenzoic acid with thionyl chloride to obtain an intermediate product, and then the intermediate product is further chlorinated to finally obtain 2,4-dichlorobenzoyl chloride.
Safety Information:
2,4-Dichlorobenzoyl chloride is an organic compound that is irritating and corrosive. Precautions should be taken during use and handling, avoiding contact with the skin, eyes, and respiratory tract. Appropriate protective equipment, such as lab gloves, goggles, and protective clothing, should be worn during the procedure. Contact with combustible substances and oxidizing agents should be avoided to prevent fire or explosion. When stored and transported, it should be sealed and kept away from fire and heat sources. ...
Application
2-Chlorobenzylamine is a chlorinated benzylamine derivative serving as a versatile pharmaceutical intermediate and organic building block. As a key precursor in the pharmaceutical industry, it is utilized in the synthesis of active pharmaceutical ingredients including antihypertensive agents, anti-inflammatory compounds, and central nervous system modulators. Its amine functionality enables diverse transformations such as alkylation, acylation, and Schiff base formation for heterocyclic synthesis. In agrochemical research, it serves as a precursor for herbicides, fungicides, and other crop protection agents. It also functions as a fragment scaffold for molecular linking and modification in drug discovery programs. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of high-purity 2-Chlorobenzylamine with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.
