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2-Fluorotoluene(CAS#95-52-3)

Chemical Property:

Molecular Formula C7H7F
Molar Mass 110.13
Density 1.001 g/mL at 25 °C (lit.)
Melting Point -62 °C (lit.)
Boling Point 113-114 °C (lit.)
Flash Point 55°F
Water Solubility immiscible
Vapor Presure 21 mm Hg ( 20 °C)
Vapor Density 3.8 (vs air)
Appearance Liquid
Specific Gravity 1.001
Color Clear colorless to slightly yellow
Merck 14,4180
BRN 1853362
Storage Condition Store below +30°C.
Explosive Limit 1.3%(V)
Refractive Index n20/D 1.473(lit.)
Physical and Chemical Properties Density 1.001
melting point -62°C
boiling point 113-114°C
refractive index 1.472-1.474
flash point 8°C
water-soluble immiscible
Use Used as pharmaceutical, pesticide intermediates

Product Detail

Product Tags

Risk Codes R11 - Highly Flammable
R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description S16 - Keep away from sources of ignition.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S33 - Take precautionary measures against static discharges.
S36 - Wear suitable protective clothing.
S37/39 - Wear suitable gloves and eye/face protection
UN IDs UN 2388 3/PG 2
WGK Germany 3
RTECS XT2579000
TSCA Yes
HS Code 29036990
Hazard Note Flammable/Irritant
Hazard Class 3
Packing Group II
Toxicity LD50 orally in Rabbit: > 5000 mg/kg LD50 dermal Rabbit > 2000 mg/kg

 

Introduction

2-Fluorotoluene o-Fluorotoluene 1-Fluoro-2-methylbenzene | CAS 95 52 3

One Line Sourcing Position

High purity 2-Fluorotoluene for pharmaceutical intermediates, agrochemical synthesis, and specialty organic chemistry applications.

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Specification

Parameter Specification
Purity by GC 99.0 percent minimum, typical batch 99.0 to 99.5 percent
Appearance Colorless transparent liquid
Molecular Formula C7H7F
Molecular Weight 110.13 g per mol
Melting Point minus 62 degrees Celsius
Boiling Point 113 to 114 degrees Celsius
Density at 25 deg C 1.001 g per mL
Refractive Index n20/D 1.473
Vapor Pressure 21 mmHg at 20 degrees Celsius
Vapor Density 3.8 (vs air)
Flash Point 8 degrees Celsius (46.4 degrees Fahrenheit)
Solubility Miscible with ethanol, diethyl ether, acetone, benzene; not miscible with water
Storage Temperature Room temperature in a cool and dark place below 15 degrees Celsius
Stock Status In Stock in US warehouse and China hub

Available Quantity and Lead Time

Regular supply: 1 kg to 30 metric tons per shipment
Lead time: 2 to 5 days for standard packaging; bulk orders require 7 to 10 days

Document Support

COA SDS HPLC chromatogram NMR spectrum Mass spectrum MS available upon request

Application

2-Fluorotoluene is a fluorinated aromatic compound valued for its unique reactivity and stability. The presence of the fluorine atom enhances the reactivity of the aromatic ring, making it a valuable precursor for various chemical transformations.

In the pharmaceutical industry, 2-fluorotoluene is widely utilized as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and fluorinated drugs. The fluorine substitution can significantly impact the pharmacokinetics of resulting drugs, enhancing their efficacy and therapeutic profile. It serves as a building block for the production of complex molecules across pharmaceutical research and development.

In agrochemical manufacturing, 2-fluorotoluene is employed as an intermediate for the synthesis of pesticides, herbicides, and other crop protection agents. It is also used in the production of diazo compounds and analytical reagents.

In specialty chemical synthesis, 2-fluorotoluene finds applications in the manufacture of coatings, dyes, and other fine chemicals. It is widely employed in organic synthesis as a precursor for various chemical transformations. The compound is also applicable in coupling reactions, drug molecule modification, and functional material synthesis. Additionally, it serves as a valuable research tool for exploring new chemical entities in drug discovery and development.

Custom Synthesis Support

We offer custom synthesis for 2-fluorotoluene derivatives including substituted analogs, isotopically labeled versions, and higher purity grades (99.5 percent and above). Custom packaging under inert atmosphere is available. Share your technical datasheet for feasibility review.

Packaging and Shipping

Available in 500 mL, 1 L, 5 L, 20 L, 200 L steel drums or IBC totes. Custom packaging such as amber glass bottles with PTFE lined caps under inert atmosphere is supported. Fastest dispatch within 7 days after order confirmation.

2-Fluorotoluene is a highly flammable liquid. UN 2388, Class 3, Packing Group II. Proper shipping name: FLUOROTOLUENES. Store in a cool, well ventilated area away from heat, sparks, and open flames. Keep container tightly sealed and store away from strong oxidizing agents and strong reducing agents. Storage temperature should not exceed 30 degrees Celsius. Keep container tightly sealed and store in a cool, dry condition in a well ventilated place.

Why XinChem

XinChem provides 2-fluorotoluene with strict control of purity and impurity profile for US customers. Our ISO 9001 certified facility monitors every batch by GC and density analysis, ensuring consistent quality for pharmaceutical, agrochemical, and specialty synthesis applications. We maintain a buffer stock in US warehouses for emergency deliveries within 48 hours. Each order includes a full documentation package: COA, SDS, and chromatograms accessible through our online portal. Our technical support team assists with handling precautions, stability under storage, and regulatory compliance including TSCA, EINECS (202-428-5), and REACH registration. For contract customers, we offer quarterly price locks and consignment inventory to reduce supply chain risk. Trusted by numerous pharmaceutical, agrochemical, and specialty chemical companies in North America. We also provide free sample evaluation for qualified R&D projects and a price match guarantee against any valid competitor quote for equivalent quality. All shipments include clear handling instructions and appropriate hazard communication to ensure safety throughout the supply chain.

FAQ

Q1 How should 2-fluorotoluene be stored safely?
A Store in a cool, well ventilated area away from heat, sparks, and open flames. Keep container tightly sealed and store away from strong oxidizing agents and strong reducing agents. Storage temperature should not exceed 30 degrees Celsius. Shelf life is 24 months under recommended conditions.

Q2 What purity grades do you supply?
A Standard grade is 99.0 percent minimum by GC. We also supply 99.5 percent grade for pharmaceutical and analytical reference applications upon request.

Q3 Is 2-fluorotoluene soluble in water?
A No, it is not miscible with water. It is soluble in ethanol, ether, acetone, benzene, and most organic solvents.

Q4 Do you provide sample quantities for method development?
A Yes, free samples are available for qualified US companies. Shipping fee applies for small quantities.

Q5 What are the main applications of 2-fluorotoluene?
A Primary applications include: (1) pharmaceutical intermediate for APIs and fluorinated drugs; (2) agrochemical intermediate for pesticides and herbicides; (3) building block for organic synthesis; (4) precursor for diazo compounds and analytical reagents; and (5) intermediate for coatings, dyes, and specialty chemicals.

Q6 What safety precautions are required when handling 2-fluorotoluene?
A 2-Fluorotoluene is highly flammable (H225). It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). It is harmful to aquatic life (H402). Use in a fume hood with full PPE including chemical resistant gloves, safety goggles, and protective clothing. Keep away from heat, sparks, open flames, and other ignition sources. Use explosion-proof equipment and non-sparking tools. In case of contact with eyes, rinse cautiously with water for several minutes.


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