2-Hydroxy-4-methoxybenzaldehyde(CAS#673-22-3)
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| RTECS | BZ2810000 |
| FLUKA BRAND F CODES | 10 |
| TSCA | Yes |
| HS Code | 29124900 |
| Hazard Note | Irritant |
Introduction
2-Hydroxy-4-methoxybenzaldehyde is an organic compound. The following is an introduction to its properties, uses, manufacturing methods and safety information:Quality:1. Appearance: 2-hydroxy-4-methoxybenzaldehyde is a white crystalline solid.3. Solubility: soluble in organic solvents such as alcohols and esters, difficult to soluble in water.Use:2-Hydroxy-4-methoxybenzaldehyde has certain pharmacological activity and can be used as an important intermediate compound for the preparation of other organic synthesis products. Due to its special properties, it can also be applied to pigments, dyes, spices and other fields.Method:The preparation method of 2-hydroxy-4-methoxybenzaldehyde can be obtained by condensation reaction of p-benzaldehyde and p-methoxybenzyl alcohol. In the specific operation, benzaldehyde and p-methoxybenzyl alcohol are mixed in an appropriate solvent, and then an acid catalyst (sulfuric acid, zinc chloride, etc.) is added, and the reaction is carried out at the appropriate temperature and time, and finally the target product is obtained by purification.Safety Information:1. 2-Hydroxy-4-methoxybenzaldehyde should be stored and operated to avoid ignition sources and avoid contact with oxidants.2. Necessary personal protective measures need to be taken during use, such as wearing protective glasses, gloves and protective clothing.4. Please comply with local laws and regulations and properly dispose of waste.
Application
2-Hydroxy-4-methoxybenzaldehyde (4-Methoxysalicylaldehyde, CAS 673-22-3) is a versatile ortho-hydroxy aromatic aldehyde widely used as a building block in organic synthesis, pharmaceutical research, and fragrance chemistry. It serves as a key intermediate for the synthesis of coumarin derivatives, flavones, and Schiff base ligands that exhibit antimicrobial, antioxidant, and anticancer activities. In coordination chemistry, its ortho-hydroxy aldehyde moiety chelates transition metals to form stable complexes used in catalysis and sensing. In the flavor and fragrance industry, it imparts vanilla-like, sweet, and woody notes to perfumes and cosmetics. It also serves as a precursor for pharmaceutical compounds targeting inflammation and neurological disorders. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of this high-purity compound with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.
