3-(1-Pyrazolyl)propionic Acid(CAS# 89532-73-0)
Introduction
Quality:
- Appearance: 3-(1-pyrazolyl)propionic acid is a colorless crystalline solid.
- Solubility: Soluble in water, alcohols and acids.
Use:
- 3-(1-pyrazolyl)propionic acid is often used as an intermediate and raw material for the synthesis of organic compounds with pyrazole groups.
- It has a wide range of applications in the preparation and study of bioactive compounds.
Method:
- The preparation of 3-(1-pyrazolyl)propionic acid can be done with the following steps:
1. Methyleneaniline is reacted with formic anhydride to form methyl 3-(1-pyrazolyl)propionate;
2. Methyl 3-(1-pyrazolyl)propionate is reacted with potassium hydroxide to obtain 3-(1-pyrazolyl)propionic acid.
Safety Information:
- 3-(1-pyrazolyl)propionic acid is generally relatively safe under normal use and storage conditions.
- Wear appropriate personal protective equipment and avoid contact with skin, eyes, and clothing during handling.
- Avoid inhaling dust and ensure that the operating area is well ventilated.
- In case of accidental ingestion or inhalation, seek medical attention immediately and provide information about the product.
- When using and handling 3-(1-pyrazolyl)propionic acid, the relevant safety operating procedures and operating guidelines should be observed.
Application
3-(1-Pyrazolyl)propionic Acid (CAS 89532-73-0) is a versatile pyrazole-based building block widely used as a pharmaceutical intermediate and research chemical. As a key component in organic synthesis, its carboxylic acid group enables esterification and amidation to construct complex molecules, making it valuable for drug discovery programs targeting anti-inflammatory, antimicrobial, and anticancer agents. It has demonstrated potential as an antioxidant, cardioprotective, and neuroprotective agent for treating cardiovascular disease, neurological disorders, and cancer. Its pyrazole moiety is essential for structure-activity relationship (SAR) studies in medicinal chemistry. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of high-purity 3-(1-Pyrazolyl)propionic Acid with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.







