3-AMINOINDOLIN-2-ONE(CAS#117069-75-7)
Introduction
3-Aminoindole-2-one is an organic compound.Quality:3-Aminoindole-2-one is a solid with a white to off-white crystalline state. It has the structure of an indole ring and a ketone group. Compounds are relatively stable at room temperature, but degradation can occur at high temperatures, strong acids, or bases.Use:3-Aminoindole-2-one has some applications in the field of chemistry.Method:In general, 3-aminoindole-2-one can be synthesized by a variety of methods. A common method is to react indole with ketones to produce 3-aminoinindole-2-one.Safety Information:
Application
3-Aminoindolin-2-one (3-aminooxindole, CAS 117069-75-7) is a heterocyclic scaffold of the indolinone family, characterized by an amino group at the 3-position and a carbonyl group at the 2-position. It is an advanced building block for pharmaceutical R&D: its derivatives are selective inhibitors of matrix metalloproteinases (MMP-2 and MMP-13), representing a drug-like chemotype for therapeutic development. 3-Aminoindolin-2-one exhibits anti-inflammatory and anticancer properties, with derivatives showing promising activity in inhibiting tumor cell proliferation and modulating inflammatory pathways. Additionally, it demonstrates significant α-glucosidase inhibition, surpassing standard drugs like acarbose and indicating potential for next-generation antidiabetic agents. Beyond medicinal chemistry, this compound is utilized in the dye and pigment industry for the development of colorants and hair dyes. Its unique structure allows for various modifications, including cascade reactions with enones or enals to form spirocyclic compounds. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of high-purity 3-aminoindolin-2-one with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.
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