3,5-Difluorobenzyl alcohol(CAS#79538-20-8)

Introduction

3,5-Difluorobenzyl alcohol is an organic compound. The following is an introduction to the properties, uses, preparation methods and safety information of 3,5-difluorobenzyl alcohol:Quality:- Appearance: 3,5-difluorobenzyl alcohol is a colorless to light yellow solid.- Solubility: It is insoluble in water but can be dissolved in organic solvents such as ethanol and ether.- Stability: 3,5-difluorobenzyl alcohol has good chemical stability.Use:- Fourier transform infrared spectroscopy validation: It is often used as a reference material in Fourier infrared spectroscopy verification.- Chemical synthesis intermediate: 3,5-difluorobenzyl alcohol can be used as an important intermediate in organic synthesis, and a series of organic compounds can be obtained through the reaction of other chemical compounds.Method:- The preparation method of 3,5-difluorobenzyl alcohol usually involves the reaction of benzyl alcohol with hydrogen fluoride or fluorine gas. For example, it can be prepared by reacting benzyl alcohol with fluorine gas at high temperatures in the presence of hydrogen.Safety Information:- 3,5-difluorobenzyl alcohol is an organic compound that needs to be stored properly to avoid contact with oxidants, strong alkalis, etc.- When operating, use appropriate protective measures, such as gloves, goggles, and a lab coat.- When handling, storing, or disposing of 3,5-difluorobenzyl alcohol, follow local safety operating procedures and regulations.

Application
3,5-Difluorobenzyl alcohol is a high-purity fluorinated aromatic building block widely used as a key intermediate in pharmaceutical, agrochemical, and material science R&D. In drug discovery, its strategic fluorine substitution pattern enhances metabolic stability, lipophilicity, and blood‑brain barrier penetration, making it a valuable scaffold for synthesizing central nervous system (CNS) agents, including antidepressants, antipsychotics, and anticonvulsants, as well as kinase inhibitors for oncology research. In crop protection, this versatile intermediate serves as a core precursor for selective herbicides, fungicides, and insecticides, improving biological activity and environmental safety. The primary alcohol group enables facile oxidation to the corresponding aldehyde or carboxylic acid, as well as esterification and ether formation, allowing rapid structure‑activity relationship (SAR) studies. Additionally, 3,5-difluorobenzyl alcohol is employed in the production of liquid crystal display (LCD) materials, specialty polymers, and fluorinated fine chemicals. Xinchem offers reliable custom synthesis, custom chemical synthesis, and contract manufacturing of this essential building block with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and dependable global supply.