3-METHYL-5-ISOXAZOLEPROPANOL(CAS#105658-49-9)

3-METHYL-5-ISOXAZOLEPROPANOL(CAS#105658-49-9) introduction

3-(3-METHYLISOXAZOLE-5-YL)PROPION-1-OL, ALSO KNOWN AS 3-METHYL-5-ISOXAZOLEPROPANOL, IS AN ORGANIC COMPOUND. The following is an introduction to its properties, uses, manufacturing methods and safety information:

Quality:
- Appearance: Colorless or light yellow crystalline solid
- Solubility: Soluble in water and organic solvents such as ethanol and methylene chloride

Use:
3-(3-methylisoxazole-5-yl)propyl-1-ol has a variety of applications:
- Catalyst: It can be used as a catalyst in chemical reactions.
- Light stabilizer: It can be used as an antioxidant and light stabilizer for plastics and rubber.
- Insecticides: have certain insecticidal activity and can be used in agriculture to control pests.

Method:
The synthesis of 3-(3-methylisoxazole-5-yl)propyl-1-ol can be carried out by the following steps:
Methylisoacetone and hydroxylamine are reacted to produce 3-methylisoxazole-5-one under alkaline conditions.
3-methylisoxazole-5-one and ethylene glycol were reacted to cyclization under acidic conditions to produce 3-(3-methylisoxazole-5-yl)propyl-1-ol.

Safety Information:
- 3-(3-methylisoxazole-5-yl)propyl-1-ol is a general organic compound and generally has certain irritation.
- Avoid direct contact with skin and eyes when using. In case of accidental contact, rinse immediately with plenty of water.
- When storing, it should be kept tightly sealed and away from fire and oxidants.
- Follow relevant safety protocols and use appropriate personal protective equipment such as gloves and safety glasses when using and handling.

Application
3-Methyl-5-isoxazolepropanol is a high-purity, regiospecific heterocyclic building block featuring an isoxazole ring with a primary alcohol substituent. It serves as a critical pharmaceutical intermediate in the patented synthesis of Pleconaril, an antiviral drug candidate for treating common cold symptoms caused by picornaviruses (e.g., rhinovirus, enterovirus). Its defined 3,5-disubstitution pattern ensures regiochemical control in subsequent coupling and functionalization steps. In material science, the compound functions as an antioxidant and UV light stabilizer for polymers such as plastics and rubber, improving their long-term durability and weather resistance. It also exhibits insecticidal activity, making it a valuable research intermediate for agrochemical development. As a versatile heterocyclic alcohol, it supports custom synthesis and contract manufacturing for structure-activity relationship studies, medicinal chemistry campaigns, and process R&D. Xinchem offers flexible custom synthesis and reliable contract manufacturing of 3-Methyl-5-isoxazolepropanol, scaled from R&D to commercial tons. Contact us for a competitive quote and global supply.