4 4′-Dichlorobenzophenone（CAS# 90-98-2)
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| RTECS | DJ0525000 |
| TSCA | Yes |
| HS Code | 29147000 |
| Hazard Note | Irritant |
Introduction
4,4'-Dichlorobenzophenone is an organic compound. The following is an introduction to its nature, use, preparation method and safety information:
Quality:
1. Appearance: 4,4'-Dichlorobenzophenone is a colorless to light yellow crystalline solid.
3. Solubility: It is soluble in some organic solvents, such as ethers and alcohols, but it is insoluble in water.
Use:
1. Chemical reagents: 4,4'-dichlorobenzophenone is widely used as a reagent in organic synthesis, especially for reactions in the synthesis of aromatic compounds.
2. Pesticide intermediates: It can also be used as an intermediate in the synthesis of some pesticides.
Method:
The preparation of 4,4'-dichlorobenzophenone is usually carried out by the following steps:
1. Benzophenone reacts with thionyl chloride in the presence of n-butyl acetate to give 2,2'-diphenylketone.
Next, 2,2'-diphenyl ketone reacts with thionyl chloride in the presence of sulfuric acid to form 4,4'-dichlorobenzophenone.
Safety Information:
1. 4,4'-Dichlorobenzophenone should take the necessary safety measures during handling and storage to avoid contact with the skin, eyes and mouth.
2. Wear protective gloves, goggles and masks when using.
3. Operate in a well-ventilated area and avoid inhaling its vapors.
4. In case of accidental contact or ingestion, seek medical attention immediately and bring a label or safety data sheet for the substance.
Application
4,4'-Dichlorobenzophenone (DCBP, CAS 90-98-2) is a symmetrically para-substituted diaryl ketone that serves as a critical building block in multiple high-value industries. As a key monomer, it is indispensable for the synthesis of high-performance polyether ether ketone (PEEK) via nucleophilic aromatic substitution polycondensation with hydroquinone, producing thermoplastics with exceptional thermal stability, mechanical strength, and chemical resistance for aerospace, automotive, and electronics applications.
In the pharmaceutical industry, DCBP is a versatile intermediate for synthesizing antihistamines, antipsychotics, and other active pharmaceutical ingredients (APIs). As a UV photoinitiator, it absorbs UV light to generate free radicals that initiate polymerization in UV-curable coatings, inks, and adhesives. It also functions as a UV absorption filter in sunscreens and plastics, a crosslinking agent for polymer networks, and a dyeing agent to enhance fabric colorfastness. Additionally, it serves as a standard reference material in analytical chemistry and as a model compound in environmental degradation studies. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of high-purity 4,4'-Dichlorobenzophenone (≥99%) with flexible scaling from R&D to commercial tons. Contact us for a competitive quote and reliable global supply.
