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4-Methyl-5-thiazolylethyl acetate(CAS#656-53-1)

Chemical Property:

Molecular Formula C8H11NO2S
Molar Mass 185.24
Density 1.147g/mLat 25°C(lit.)
Melting Point 112 °C
Boling Point 117-118°C6mm Hg(lit.)
Flash Point >230°F
JECFA Number 1054
Vapor Presure 0.00774mmHg at 25°C
Appearance Liquid
Specific Gravity 1.147
Color Clear brown
pKa 3.26±0.10(Predicted)
Storage Condition 2-8°C
Refractive Index n20/D 1.51(lit.)
Physical and Chemical Properties Colorless liquid. Boiling point 105-108 °c (533pa). Presented as nuts, sweet fruits, Woody, and roasted aromas.

Product Detail

Product Tags

Hazard Symbols Xi - Irritant
Risk Codes 36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39 - Wear suitable gloves and eye/face protection
S24/25 - Avoid contact with skin and eyes.
UN IDs UN 3334
WGK Germany 3
TSCA Yes
HS Code 29341000

 

Introduction

4-Methyl-5-(2-acetoxyethyl)thiazole is an organic compound with the structural formula CH3C(O)OCH2CH2SCH3, also known as Me-AET. The following is an introduction to the properties, uses, preparation methods and safety information of this compound:- Properties:- Appearance: 4-Methyl-5-(2-acetoxyethyl)thiazole is a colorless to light yellow liquid. - Soluble: Soluble in most organic solvents such as ethanol and dimethylformamide. Usage:- It can also be used as a chemical reagent in some applications in life science research, such as antimicrobial activity research, etc. Preparation method: -4-methyl-5-(2-acetoxyethyl)thiazole is generally prepared by Meisenheimer aromatic sulfide synthesis. The specific steps include reacting 4-methyl-5-diethylaminophenol with acetyl chloride in the presence of a base to form a target product. Safety Information:- Although there is less information about the toxicity of this compound, as an organic compound, its application and operation should follow safe laboratory practices. - When using, storing and handling, observe relevant safety measures to prevent contact with the skin, eyes and respiratory tract, and avoid contact with substances such as oxidants.

Application
4-Methyl-5-thiazolylethyl acetate (Sulfurol Acetate, FEMA 3205, CAS 656-53-1) is an organosulfur compound with a powerful nutty, roasted, sweet, meaty and beefy aroma. In the flavor industry, it is a high‑impact savory flavor ingredient used to create coffee, cocoa, peanut, roasted nut, gravy, broth and meat flavors for candies, baked goods, meat analogues, seasonings, soups and dairy products. Its allowed usage in beverages, baked goods, candy, frozen dairy and gelatin reaches 55 mg/kg. In pharmaceuticals, it serves as a key building block for drug APIs including anticancer and antiviral agents. In agrochemicals, it is an intermediate for herbicides and pesticides with effective crop protection properties. The compound is also used in cosmetics as a fragrance ingredient to impart warmth. As a biochemical tool, it inhibits glutamate decarboxylase and exhibits antioxidant and antimicrobial activities. Xinchem offers high‑purity 4‑Methyl‑5‑thiazolylethyl acetate with reliable custom synthesis and contract manufacturing, scaled from R&D to commercial tons. Contact us for a competitive quote today.


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