4,5,6,7-Tetrahydrobenzo[d]isoxazol-3-ylaMine)(CAS#1004-64-4)

Introduction

4,5,6,7-Tetrahydrobenzo[D]isoxazole-3-amine is an organic compound.Properties: 4,5,6,7-tetrahydrobenzo[D]isoxazole-3-amine is a white solid with a special molecular structure. It is a nitrogen-containing heterocyclic compound that may have some special chemical properties.Method: The method for the preparation of 4,5,6,7-tetrahydrobenzo[D]isoxazole-3-amine may include an organic synthesis method to convert the raw material into a target product through a specific reaction pathway.When handling and using, strictly follow chemical safety operating procedures, wear personal protective equipment, and store them in a safe, sealed container, away from ignition and oxidants. If the compound needs to be used or handled, detailed safety information should be consulted with the chemical supplier or professional body.

Application
4,5,6,7-Tetrahydrobenzo[d]isoxazol-3-amine (3-Amino-tetramethylen-isoxazol, CAS 1004-64-4, MFCD19205004, purity >95–98%, C7H10N2O, MW 138.17) is a versatile bicyclic heterocyclic amine and a key isoxazole-based pharmaceutical intermediate. As a privileged scaffold, it serves as a critical building block and advanced fragment for medicinal chemistry discovery campaigns targeting oncology, neurology, and infectious diseases. In drug discovery, this modulator serves as a key precursor for the synthesis of patented tetrahydrobenzisoxazole and tetrahydroindazole derivatives as potent regulators of mitotic motor proteins for anticancer research (WO‑2008080455‑A1, US‑2010022530‑A1). This compound also acts as a selective inhibitor of glial GABA uptake and glutamate transporters, showing promise as a candidate for neurological disorders including epilepsy and neuropathic pain. Biological studies have demonstrated its low micromolar activity against both Gram‑negative and Gram‑positive pathogens. As a result, this scaffold is also being explored for its antiviral, anticancer (apoptosis induction), and CNS (antidepressant/anxiolytic) properties. Xinchem offers flexible custom synthesis, custom chemical synthesis, and contract manufacturing of high-purity this product from R&D grams to commercial tons, with reliable global supply. Contact us today for a competitive quote.