5-Bromoindole(CAS#10075-50-0)

Chemical Property:

Molecular Formula	C8H6BrN
Molar Mass	196.04
Density	1.5466 (rough estimate)
Melting Point	90-92 °C (lit.)
Boling Point	228.5°C (rough estimate)
Flash Point	145.5°C
Solubility	126mg/l (calculated)
Vapor Presure	0.000738mmHg at 25°C
Appearance	White-like crystal
Color	White to light brown
BRN	112877
pKa	16.04±0.30(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.6550 (estimate)
MDL	MFCD00005670
Physical and Chemical Properties	trait-like white crystals
Use	Used as a pharmaceutical Intermediate

Send email to us

Product Detail

Product Tags

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S24/25 - Avoid contact with skin and eyes. S37/39 - Wear suitable gloves and eye/face protection
WGK Germany	3
HS Code	29339990
Hazard Note	Irritant

Application
5-Bromoindole (CAS 10075-50-0) is a key heterocyclic building block widely used in medicinal chemistry and pharmaceutical research. The bromine atom at the 5-position enables efficient cross-coupling reactions (Suzuki-Miyaura, Buchwald-Hartwig, Sonogashira) to introduce diverse aryl, heteroaryl, or alkyl substituents, while the indole core serves as a privileged scaffold for bioactive molecules. This compound is extensively utilized in the synthesis of selective kinase inhibitors targeting cancer, inflammation, and neurological disorders, as well as serotonin receptor modulators, antiviral agents, and antimicrobial drugs. It also serves as an intermediate for natural product analogs and agrochemicals. High purity ensures reproducible results in high-throughput screening and SAR studies. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of high-purity 5-bromoindole with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.